Tretinoin for Lines in Under Eye Area?

The package insert warns patients not to place Retin A in the eye area, around the mouth, and in the upper naso-labial folds (smile lines). However, I think that if you are careful, you should be able to place tretinoin into the crow's feet area. However, if you notice irritation developing stop, apply it in this area every third day. Creams are going to be much better tolerated than gels or ointments.