Can 1% Tretinoin Cream Lighten Hypopigmentation?

I believe you mean Hyperpigmentation... Hypopigmentation means loss of pigment, as in white spots; hyperpigmentation means darkening of skin, like melasma, brown spots, etc. So only hyperpigmentation needs to be lightened. 1% Tretinoin can help lighten hyperpigmented areas, but it's usually minimally effective because the pigment is much deeper and the medication can only penetrate so deep into the skin layers. Usually for patients with hyperpigmentation I recommend IPL or... more