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Can You Use Tretinion and Hydroquinone Together Interchangably?

How can you udon both of these cream at the same time safely and correctly to achieve opitimum results

Doctor Answers (3)

Tretinoin and hydroquinone


Tretinoin and hydroquinone are both used for fading brown pigmentation.  They are often prescribed as a mixture together with a cortisone cream for maximal results.  It is important to use sun protection to prevent repigmentation.  You should consult a board certified dermatologist to assess your skin and ensure you are using the correct products.

Toronto Dermatologist
5.0 out of 5 stars 16 reviews

Tretinoin (Retin-A) and Hydroquinone together


Retin-A and Hydroqinone work well together to treat melasma.  There is a product called Tri-Luma that has both of these agents along with a topical steroid to help decrease irritation.  You don't have to worry about the optimum combination since it is a single application product (each day).  Tri-Luma is currently unavailable, but it can be compounded by a pharmacist.  Hope this helps!

Curt Samlaska, MD
Las Vegas Dermatologist
5.0 out of 5 stars 1 review

RetinA and Hydroquinone...


For optimal results I recommend using both products together in the evening before you go to bed.  RetinA will help Hydoquinone penetrate better and give you better results.

Consult your physician prior to starting these products. 

Hope this helps.


Dr. Grant Stevens        Marina PlasticSurgery Associates          Marina del Rey, CA         The Institute


Grant Stevens, MD
Los Angeles Plastic Surgeon
4.5 out of 5 stars 67 reviews

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