Side Effects from Botox for Under Eye Wrinkles?

Botox does not cause thinning of the skin or reduction of collagen. In fact because if relaxes the muscles that cause the wrinkle, you tend to have less wrinkles over time as your collagen naturally regenerates. While Botox is excellent for crows-feet and brow wrinkles, there needs to be caution when Botox is given directly to the lower eyelid itself. The muscles in that area are responsible for eye closure and the pumping away of your natural tears. If the area is not treated very... more

The only risk that is different for injecting the undereye wrinkles with Botox is that the injector must be very careful with dosing, placement, and selecting the correct candidate. If you don't have strong enough lower eyelid tension, you can get ectropian, which is when the lower lip everts. Although this will be temporary, it's a problem for several weeks with tearing and possibly drying of the eye. No skin issues can be caused by this injection.

Dear Luci BOTOX does not cause these issues. However, it is not the best product for reducing the lower eyelid lines. This is because the muscles that are making those lines are also supporting the lower eyelid. When sufficient BOTOX is used to improve the lower eyelid lines, there can be a weakening of this muscle which can cause the lower eyelid to fall. This weakness of the lower eyelid can be bothersome. A great alternative is to fill the lines with Restylane. This product lasts much... more

Botox treatments are not typically associated with a change in collagen or thinning of the skin. Botox effects are always temporary. The most common side effect from Botox around the eyes is ptosis and mild temporary bruising. 

To the best of my knowledge, there is no reason to suspect that botulinum toxin will cause thinning of the skin or a reduction on collagen in they eye area.