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Why Wouldn't Wydase Work to Dissolve Juvederm? (photo)

Four months ago I had a PA inject Juvederm Ultra Plus XC in my smile lines and lips. I'm 29 and didn't have deep lines but was told the juvederm would prevent future wrinkles. I now have unnatural swelling and hard lumps around my mouth that look very unnatural and cause sagging skin under my mouth. I've had four different injections by two different doctors of wydase with no improvement. Are these lumps permanent? Are any doctors in south Florida experienced with treating these complications?

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age 25-34 lips hardness lumps smile lines swelling

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9 Doctor Answers | Asked by depressedgirl in rhode island

Doctor Answers (9)
Community Comments (2)

Why Wouldn't Wydase Work to Dissolve Juvederm?

Wydase dissolves hyaluronic acid which is what Juvederm is made of so the question is whether the lumps are granulomas or perhaps what was injected isn't an HA filler. You might consider going to a Derm or a Plastic and cosmetic surgeon in your area for a biopsy of one of these lumps for a path diagnosis.

Why Wouldn't Wydase Work to Dissolve Juvederm?

Many issues at play here. First why have a PA inject? Than are you sure it was Juvederm? Are you sure the Wydase was injected correctly? And in enough of an amount. Finally you must consider excision, but the issue of a scar must be considered. Understand there are A:WAYS risk with ANY cosmetic procedure.

Hyaluronidase Not Effective

Hyaluronidase injected 4 times without any improvement may signal a granuloma that may not be as responsive to hyaluronidase.

Juvederm plus requires at least twice as much hyaluronidase to dissolve

Juvederm Plus takes at least 2-3 times as much hyaluronidase to dissolve it as other hyaluronic acid products, including Juvederm Ultra. If only a small amount of hyaluronidase was used each time, it may not have been enough. By the way, while Botox can sometimes prevent wrinkles, fillers do not, they simple conceal them. Dr. Kenneth Beer is an excellent cosmetic dermatologist in the Miami area. Good luck.

Lorrie Klein, MD

145 reviews

Laguna Niguel Dermatologic Surgeon

www.ocdermatology.com

Fillers and hyaluronidase

If the filler injected was a hyaluronic acid, then it shoudl be able to be dissolved by hyaluronidase( Wydase). It could be a hematoma or another product that was inejected.

Steven Wallach, MD

12 reviews

Manhattan Plastic Surgeon

Melting Juvederm

If the lump is caused by Juvederm or another other hylauronic acid, then the Wydase will melt it. It is possible that what you are observing is not from the Juvederm directly but possibly swelling from the injection, a small hematoma, an inflammatory reaction or something unrelated. Are you sure it was Juvederm they injected and not Radiesse or other non-HA filler? Good Luck.

Why Wydase didn't dissolve Juvederm

I understand you have lumps around your mouth that you believe are Juvederm, not dissolving with repeated injection of Wydase. Reasons may be: Lumps are pre-existing muscle/fat bulges that are now drawing your attention more than before Not enough rounds of Wydase - Juvederm is durable stuff! You should see SOME change with each injection, however. Lumps are a non-Juvederm filler Wydase isn't real/effective Wydase... more

Why didn't Wydase work to dissolve Juvederm?

There are many variables. If you have a before picture it might be good to compare side by side. Is it possible that some of it, is a fat pad that was there before? If not you might ask whether it's actually Juvederm or was the Wydase injected in the correct place? The good news is that any HA filler is temporary so if it is Juvederm it will resolve on it's own over a few months.

Sam Naficy, MD

80 reviews

Seattle Facial Plastic Surgeon

www.seattleface.com

Dissolving Juvederm, and no changes?

4 rounds of Wydase (hyaluronidase) is a lot to see absolutely no changes. In my experience with using it, it may take 2 times or so, but immediate improvement is noted. If you've had nothing change, simply you must not have had Juvederm, or you may have had gray market Juvederm...which wasn't hyaluronic acid. HA is dissolved by hyaluronidase, period, so if it's not changing, the filler wasn't Juvederm.

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Comments (2)

RedRoxie 12 Mar 2013

So here's the thing about wydase, vitrase, whatever they want to call it. IT DAMAGES YOUR NATURAL TISSUE. That's what you have now. It breaks down the natural fibers in your skin. So you are left with sagging tissue under the skin. These doctors are idiots and will tell you it doesnt damage the skin and everything will return to the way it was NO IT DOESN"T I had restylane over injected by Dr Bradford Patt in Houston. So much that it created distortion and made me look weird. He said he could reverse it-no problem. I had a facelift several years and the wydase UNDID my tissue and my facelift fell apart. Just spent over 30K to have my face fixed. It also dissolved my fat-it ruins the skin and these morons just don't get it. DO NOT INJECT ANYMORE filler or hyaluronidase. These doctors should be shot up with this crap so they can see what it does. Hope things improve but don't count on it.