Ask a doctor

Does Retin A Require Inflammation to Work?

Hi, I have been using retin A for the last 6 months. I know that inflammation is required for the body to heal itself. So is inflammation required in the retin A mechanism to thicken the dermis? Or does retin A simply signal the body to produce a more youthful form of collagen without the use of inflammation? Thanks

Doctor Answers (2)

Retin A Collagen Production

+2

Retin A has been proven to induce new collagen production.  However, the mechanism of action for collagen production is unrelated to the skin irritation many patients experience when first using Retin A.  Thus, experiencing irritation from Retin A has no correlation to the underlying dermal collagen production.  As always, I recommend being evaluated and treated by a board certified dermatologist so that a skin care regimen can be designed for your individual condition.


Houston Dermatologist

Retin A

+1

Retin A causes redness and irritation to the skin initially. This is the inflamation that causes new collagen to be formed and for the skin to improve.

Samir Shureih, MD
Baltimore Plastic Surgeon

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.