Why Does Restylane Swell So Much More Than Juvederm? Doctor Answers, Tips
Restylane: Q&A
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Why Does Restylane Swell So Much More Than Juvederm?

I had restylane in the past for my lips and had a terrible time with swelling. The most recent treatment I switched doctors and she used Juvederm. I didn't swell at all and love the results. Why did I have so much unattractive swelling with restylane in the past? And why would a doctor choose restylane over juvederm?

24 Doctor Answers | Asked by Mama in the House in Los Angeles, CA
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Swelling after Restylane v. Juvederm

Both Restyllane and Juvederm contain the same basic chemical component but are marketed by different companies. in all likelihood, the critical distinction between your reaction to the two treatments is the technique used by the physicians. Both products should produce similar results; as for physician preference, it is like the difference between Coke and Pepsi. Some physicians opt for Juvederm because of preferential pricing and others for Restylane for precisely the same reason! more
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Restylane - Why Does Restylane Swell So Much More Than Juvederm?

I suspect that it's due more to the injection technique (that particular time) than to the choice of filler. In my experience there is no noticeable difference between these two fillers and it appears that most physicians use them almost interchangeably. If there was a difference to that degree, it seems likely that it was from specifics of the injection itself. And in the lips that's not too sup rising; the lips are so vascular (ie, have such a large blood supply)... more
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Juvederm or restylane for the lips

Both Juvederm and Restylane can cause, in very rare circumstances, excessive swelling in the lip areas. There may not be a difference in the two products in terms of swelling. Restylane is more particulate and can be used when greater structure is needed to lift a tight crease but Juvederm is nice to provide a smooth lip augmentation. Restylane also produces smooth lips though, and ultimately, it is up to the physician to decide what they prefer to use and answer your... more

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Restylane Swelling vs. Juvederm

The difference in swelling you experienced had much more to do with injection technique and the M.D. performing the injection rather than any difference between Restalyne and Juvederm.
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Restylane does give slightly more transient swelling than Juvederm

Both are excellent fillers and in most places can be used interchangeably however I do prefer Juvederm Ultra as lip filler as I find it is more pliable and gives a softer look and feel and Restylane in the tear troughs, where it has less capacity for traveling.
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Swelling after Restylane or Juvederm

I have seen no difference in the swelling caused by either Restylane or Judederm. I believe injection technique and the amount of product used make the most difference. I try to limit the number of times that that I put the needle in the lips to 2, because I have found tha the trauma of multiple pokes is the biggest cause of swelling.
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Swelling is usually minimal after Restylane or Juvederm.

My experience with Restylane is that some patients had a lot of swelling years ago. I have not had that problem more recently. In my hands Juvederm and Restylane are nearly interchangable and have very similar results and side effects (rare swelling for a few days). You may be one of the rare individuals who reacts to Restylane. Your doctor would have no way of knowing that. Now that you know that you are sensitive to Restylane remember to let your doctor know... more
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Restylane vs. Juvederm swelling with lip injections: likely the doc, not the stuff.

If you notice much less lip swelling with Juvederm injections than you had with Restylane into your lips, it is most likely the amount used and the exact placement and technique of the doctor injecting. In fact, if you look around RealSelf, you will see that most answer say Juvederm swells MORE than Restylane. I think they are about equal. If you like the results of this doctor, great! With less initial swelling, you may also decide that in a few weeks, your results aren't as noticeable... more
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Swelling after Restylane vs Juvederm

I use both products in the lips, but have seen little consistent difference in swelling with Restylane and Juvederm. In fact, when I inject the lower eyelid grooves I prefer restylane which attracts less water and causes less swelling. Your experience was probably related to technique or you just had a bad day with the first injection.
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Restylane or Juvaderm for Swelling in Lips?

Hi Mama. We would guess that the swelling previously had more to do with technique than with the product. Restylane and Juvederm are very similar products and we find them to cause the same amount of swelling when injected into the same area of the same patient. We wonder if the technique with the latter practitioner was superior and the reason for less swelling. Either way, at least now you know what combination of practitioner and product work well. more
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Restylane and swelling

Restylane is composed of hyaluronic acid. In my clinical practice, I have not noticed that Restylane swells up more than Juvederm. Some patients develop small urticarial like bumps after Restylane injection, but this is temporary and resolves quickly. The swelling associated with fillers have to do with a variety of reasons, including injection technique (for example, if I were to take a syringe and jam it into your skin and keep doing that 100 times, you will swell more than if I were to... more
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Restylane and Juvederm Cause Similar Swelling

Although both Restylane and Juvederm are different hyaluronic acids I have not noticed any difference in patient response. In my experience swelling and bruising after injections are often related to 1. where the filler is placed, and 2.patient related issues. 1.The closer the filler is placed to the eye, bruising is a possibility, due to the thin skin and multitude of blood vessels. 2. Patients who swell after a treatment should watch their salt intake three days before the... more
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Restylane vs Juvederm

Both Restylane and Juvederm are made of hyaluronic acid. This is a substance that attracts water and therefore gives volume to the injection site. That itself is a form of swelling. However, neither of these products usually causes a lot of swelling. You may simply have had an unusual response to one injection session or technique.
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Swelling after Restylane / Juvederm

I have been injecting Restylane since it was FDA approved in 2003 and Juvederm since it was FDA approved in 2006. I have not noticed that either product causes more swelling than the other. If you had the products injected by two different injectors, it is likely that different technique between the injectors explains the difference in your results.
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Does Restylane Swell More Than Juvederm

I have been injecting lips for the purpose of cosmetic enhancement for over 25 years and began using Restylane and Juvederm as soon as they reached the US market. Restylane & Juvederm are both made of hyaluronic acid, a natural component of the skin that progressively decreases with age. Hyaluronic acid is the fluid matrix that provides stabilization to the intercellular spaces that contain collagen and elastic fibers. The typical side effects associated with hyaluronic acid... more
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Restylane and Juvederm are comparable products

If Restylane swells more than Juvederm it should be by a marginal amount. The lips are very vascular and highly reactive to needle based filler treatments and can swell dramatically with any filler treatment. Since both are comparable, we actually use more Juvederm than Restylane, next time request Juvederm.
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Restylane may swell more than Juvederm

I have personally had both Restylane and Juvederm in my lips and also found Restylane swelled more than Juvederm. I had the same injector both times (me!) so it was not due to injector technique. Where I practice in Orange County Juvederm and Restylane lip injections are very popular and I see many patients for this. I have not consistently found a difference in my patients however and very few have mentioned either one being a problem. A rougher technique, more injection... more
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This most likely had much more to do with the doctor than the particular filler used.

The two fillers Restylane (Medicis, Inc.) and Juvederm (Allergan, Inc) are relatively comparable products. In my hands, there seems to be slight more post procedure swelling with Juvederm than Restylane but I have never scientifically studied this issue. For some injectors, the "smoothness" of Juevederm means a lower incidence of lumps and bump when treating structures like the lips. For other injectors, Restylane holds better in the tissue than the Juvederm.... more
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Difference in swelling with Restylane vs Juvederm usually slight

Both Restylane and Juvederm are good products and both are based on the same molecule, hyaluronic acid or HA. It is a naturally occurring molecule but broken down quickly so it is altered through a process called crosslinking, which increases the particle size. However, the crosslinked part has to be diluted into a little bit of the uncrosslinked part in order to make it smooth enough for injection. Because HA's attract water, especially the uncrosslinked portion, the more of this the... more
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There is no difference in the swelling

I been using both products and have not seen any difference in the swelling. you may have different result due the injection techniques.
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Restylane versus perlane

There may be slightly more swelling with Restylane as the molecule tends to attract more water initially. However you may also just have more or less swelling due to unintentional variation in technique (sometimes in the lips there are vessels that can be hit that result in swelling and bruising). Regardless both fillers should yield equally excellent results with few side effects.
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Swelling from Restylane vs Juvederm

Actually I have seen the exact opposite effect in my patients to the point where I don't even use Juvederm anymore. Especially true in the undereye area I have seen Juvederm swell much more than Restylane.
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Swelling with injectables

Swelling with any injectable is unpredictable. After all you are sticking a needle below the skin with no way to see the vessels below. I do thousands of injections and see very little swelling. Of course, the very vascular lips will be at highest risk. My experience is tha the product has little to do with but, the injector does.
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Restylane® contains more free hyaluronic acid, so swells more sometimes

Restylane® and Perlane® are fomulated with more non-crosslinked hyaluronic acid [HA] which is used as a gelling agent to keep the slurry of particles of cross-linked HA in suspension during the period of time between manufacture and injection. This non-crosslinked HA binds additional tissue water after injection, and sometimes this adds to the swelling which can occur after any injection. Your body disposes of the non-crosslinked HA in the filler within a day or two, so I would... more
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