There may be more bruising when on NSAIDS with Restylane
While it is safe to have Restylane injections while on an anti inflammatory medication, the so called NSAIDS carry an increased risk of bruising due to their platelet inhibitory effects. I recommend stopping these and substituting acetomenophen (tylenol) for example, about 10 days before injections.
You don't mention which antiinflammatory medication you are taking, but I'll assume it's an NSAID (such as Motrin or Aleve). In such case, the only risk of having Restylane (or any filler) injected is temporary increased bruising immediately after. It should not affect the result of the Restylane. I have had patients note decreased bruising and/or faster resolution if they take arnica montana or bromelain tablets right before and for several days after I inject...
There should be no problem for you to get Restylane while taking anti-inflammatory drugs. Depending on the medication, there might be an increased risk of bruising, and with others a theoretical increased risk of infection. I think if the disease is stable and you have been on the medications for a while, the risk would be small.
Restylane safety while on anti-inflammatory medication.
If you are on aspirin-related medication including sulfasalazine (whose break-down products include an aspirin-like component), there is an increased risk of bruising. Use of such anti-inflammatories is not in itself, however, a contra-indication to having filler procedures such as Restylane.
Restylane and Juvederm can be done cautiously with antiinflammatory medicines
There is no interaction between the antiinflammatory medicines and the hyaluronica acid fillers such as REstylane and Juvederm, but there may be significant bruising because many antiinflammatory medications create easy bleeding. A very rare complication would be a hematoma or blood collecting underneath the skin which could increase the risk of infection and even the formation of a persistent hard lump.
If the medication you are taking does not prolong your bleeding, there will be no risk of your using any Hyaluronic acid fillers (Restylane,Perlane,Juvederm etc). Antiinflammatory agents often prolong bleeding and may result in some bruising with injectable agents such as Botox or fillers.
Dr. Peter Aldea