Can I Use Restylane Without Botox for Glabellar Lines?

Given your situation, we would most likely be willing to use Restylane alone without the Botox.  To know for sure, we would have to see the region you want treated.

It is not an optimal solution without Botox, but if your MD has cleared you for dermal fillers and not the Botox, it is a viable alternative. 

While Botox is the best treatment for glabellar lines, Restylane and Juvederm are the second best treatment. While I don't mean to disagree with your Lyme disease specialist, I'm not sure why a small amount of Botox in this area would be a problem for you.  There is no contraindication between Lyme disease and the use of Botox that I am aware of.  Make sure you go to a specialist who is very experienced in injecting this area.  If a filler is injected too deeply in the glabellar area there can be serious side effects.  An experienced filler can do it very safely however.

yes, Restylane or Juvederm Ultra may be used in the glabellar region for creases if your doctor suggests that you shouldn't get Botox because of the Lyme disease. The amount of product must not be excessive as this is a risk area for a complication that has been reported a few times. If too thick a filler is used, or too much volume of filler in the glabella, there can be a reduction of blood flow to a sizable region of the mid forehead and that can result in a large scab that can lead to permanent scarring.