Can Restylane in a Blood Vessel Cause an Embolism That Can Cause Death? Doctor Answers, Tips
Restylane: Q&A
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Can Restylane in a Blood Vessel Cause an Embolism That Can Cause Death?

I'm about to have the injections to my 11 lines in my forehead and have read that this area is somewhat at risk for blood vessel injection. If that happens and an embolism occurs what is the worst that can happen, and how can it be controlled?

6 Doctor Answers | Asked by Saint Clair Shores in Saint Clair Shores, MI
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Great question. Hope everyone is paying attention.

Dear Saint Clair Shores BOTOX, Dysport, and other Botulinum toxin preparations are safe for the 11 lines area between the eyebrows. The treatment is extremely safe and proven effective.  It is possible to inject into a blood vessel in this area, and the tiny amount of agent that will get into the blood stream is not associated with systemic side effects.  Even the FDA which recently required so-called black box warnings which for Botulinum toxin agents, has said that... more
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Risk of embolus after filler injection

The risk of an embolus after a filler injection is extremely rare.  While it could happen it would be like get struck by lightening
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Restylane and Juvederm in forehead and risks

There has not been a case of an embolus causing death that I am aware. Restylane and Juvederm would be safe (nothing is without risk) for the glabella region in the forehead between the eyebrows (the "11") but Perlane, Juvederm Ultra Plus and Fat Injections, which are thicker fillers,  increase the risk of interference of blood flow to the middle forehead which can cause ulceration, necrosis (death of the skin) causing scarring and shoud not be used in this region. more

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Restylane injections can rarely cause blood vessel occlusion but not death

Complications from injections of fillers in the glabellar area are usually rare.  When a filler is accidentally injected into a blood vessel, occlusion of that vessel can occur with the resultant interruption of blood supply to tissues.  If that happens, the tissue supplied by that blood vessel may die or undergo necrosis.  That includes skin and in very rare cases, the eyes. Normally, this occlusion or blockage can be dissolved quickly with hyaluronidase.  If... more
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Restylane in a Blood Vessel Cause an Embolism

Interesting question but this result would be like winning the lotto two times in a row. Anything is possible but the probability of this occurring is soooooooo low that I would not even entertain these thoughts. 
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Restylane is a safe filler

First let me point out that the usual first line approach to the vertical lines between the eyebrows is Botox rather than a filler because it is hyperactive muscles in that area that cause the wrinkles to form. If that doesn't completely correct it then a filler such as Restylane is considered. The complication you are describing where the filler can go into a blood vessel is very rare and the result could be an area of skin that dies, but it would not cause death of the... more
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