I received botox (eyes/forehead) the morning prior to conception. I am now 6 weeks pregnant. What are the risks to my baby?
I Received Botox the Morning Prior to Conception. What Are the Risks?
Doctor Answers (7)
Risks to the baby of receiving Botox injection prior to conception
We don't know what effect any cosmetic procedure done during pregnancy may have on the baby, so it's not recommended that a woman who is pregnant or trying to become pregnant have any such procedures done.
But if it happens accidentally, what do we do? We can analyze the risk of anything bad happening. In your case, I don't believe there would be any harm to the baby if you had Botox injections within hours before conception. Here are some facts to support this:
- After fertilization (sperm entering the egg), the embryo spends about a week swimming around the uterus prior to implantation and establishment of a blood supply from mother to baby.
- The very primitive beginnings of a nervous system in humans start forming around week 2 after conception.
- Botox works by binding to a receptor molecule on a motor nerve cell (a nerve cell that sends a signal to the muscle to contract) and after being internaized by the nerve cell, preventing the release of a neurotransmitter (acetylcholine, in this case) from the nerve cell into the junction between the nerve and the muscle. The actual nerve cells that would be affected by the Botox would not be formed for several weeks after your Botox injection took place.
- Also, more than 90% of Botox molecules are ireversibly bound to their site of action within 1-3 hours after injection, so the chances that there will be any molecules swimming around even several hours later are exceedingly small.
First off, congratulations on your pregnancy! While the fetus is only in the early cell stages, there shouldn't be any complications. I always recommend telling your OB that you had botox/dysport the day before you conceived.
Best of luck to you!
Botox Before Pregnancy?
Hi Betsy. We're not sure that we can add much to the very comprehensive answer made by Dr. Altman other than to say that we believe you should try not to lose sleep over this. That is not meant to minimize your concerns but rather to help you feel better about the situation.
Although there are no studies involving pregnant women or women trying to get pregnant that are also using Botox, the chance of the Botox making it to the fetus would be exceedingly low based on the localized nature of the product.
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Botox injections prior to conception
Within 20 to 90 minutes after Botox is injected, botulinum neurotoxin type A can be detected inside the motor nerve endings. Therefore the muscles and nerve endings take up Botox very quickly before it can spread far from the injection site. I tell my patients they are free to do anything they choose 1 1/2 hours after their injections. This would include conception.
Congratulations on your pregnancy.
Botox during Pregnancy
Since Botox studies on pregnant women are not done, we do not know the exact risks to the fetus. Therefore, Botox is not recommended during pregnancy.
However, in my personal opinion, it is very unlikely, if not improbable that the very small amounts of Botox that we use to inject into your face (where it attaches locally to facial muscle receptors) is likely escape this area and travel to a distant developing embryo in any appreciable amount, as to cause harm to the developing embfryo. But, please tell your OB, good luck and congratulations on your pregnancy.
Botox and Pregnancy
Although we don't know the exact risks with botox and pregnancy, I think that you will be fine. I would never recommend botox during pregnancy, or while breast feeding. However, having botox just before you conceived is unlikely to affect the fetus at such a very early stage. If you think about the mechanism of Botox, it works on the receptor complex between the nerves and the muscles. While your fetus is only in the early cell stages, there shouldn't be any interactions. I would recommend that you tell your OB that you had botox the day before you conceived, but I am hopeful that it won't affect the development or health of your baby. Good luck and congratulations on your pregnancy.