Radiesse vs. Restylane, which is best for lip enhancement?
Answers (2)
Juvederm vs LiveFill for lip augmentation
Radiesse is not FDA approved for injection in the lips. It is a hydroxyapatite, a bone-like material, based. The FDA approval it did receive was with conditions, and for the nasolabial folds. Dissenting members of the FDA commission noted that after its approval, doctors would most likely start using it for unapproved "off-label" uses, such as the lips, which by your question has obviously already occurred. Extreme pain on injection, lumpiness and granuloma formation (permanent lumps) are the usual problems with Radiesse.
Restylane is made of hyaluronic acid and is a fine lip filler. I personally prefer Juvederm or Perlane for temporary filling of the lips (usual duration 4-6 months). They tend to be more supple for lip tissue and less "clumpy" than Restylane.
For patients wishing more permanent lip augmentation, we like our technique of LiveFill (autologous nontraumatized fat-fascial grafts). The disadvantage of LiveFill lip augmentation is the small numbers of doctors performing this technique, the necessity and expense of having an outpatient procedue. Advantages include permanent results, reduction in lip lines, no changes over time as filler wears off, and a high published safety profile.
I personally avoid all semi-permanent fillers in the face because of the chance of chronic inflammation, granuloma formation and lumpiness.
Radiesse is a no-no in the lips.
The short answer is that Restylane is much better for lip enhancement.
Radiesse (also known as Radiance) is a synthetic filler made from calcium hydroxyapatite, similar to bone. It is injected for soft tissue augmentation and fine lines and wrinkles. Using Radiesse in the lips is asking for trouble as it comes with a high risk for lumps and bumps (granulomas).
If someone wants to inject Radiesse into your lips, I suggest you smile politely, say no thank you, and then run (don't walk) the other way.






unregistered guest
16 Jan 2009
as a patient that got injected with radiesse i cant but be gratefull to the doctor that allowed me to have the best soft big lips ever.never in my life i had so many compliments about my big even not lumpy lips that lasted almost one year.
154 posts
2 Mar 2008
I couldn't agree with Dr. Hoenig more. Radiesse should never be a product that is used for lip augmentation. I've come across several patients that received this treatment at another facility only to be left with very noticeable and palpable nodules/lumps. A good practitioner will be very aware of which products are the safest and most appropriate for each particular area of the face. Restylane, by far, is the best choice for lip augmentation and shaping.
109 posts
3 Mar 2008
Radiesse does NOT belong in the lips! It is made up of calcium hydroxyapetite microspheres that are a HUGE RISK to form granulomas in the lips (unsightly lumps and bumps). However, Radiesse is excellent when used as part of a volumalift in the nasolabial folds and to help define cheeks and jawline. Restylane is hyaluronic acid and makes an excellent filler in the lips. It is my preferred lip enhancement filler. Radiesse should NEVER be used in the lips! REPEAT... Radiesse should NEVER be used in the lips! Restylane is a natural appearing filler when used appropriately. Medicine is an art. You want a provider with experience in making people look their best rather than in merely emptying a syringe! There is a difference. :-)