Is Radiesse Safe to Use with a Diagnosis of Scleroderma/polymyositis?

All fillers stimulate collagen production by the overlying skin. That includes Radiesse, even though it is "immunologicelly Inert". It is difficult to predict if, once stimulated into producing new collagen, the Fibrocytes of a patient with Scleroderma would not continue to do it excessively. This is purely a theoretical concern. I would be less affraid of injecting autologous fat, knowing that anything that distends the skin long term, may stimulate the... more

I would not be willing to inject Radiesse into a patient with Scleroderma. Sculptra, and to a lessor extent Radiesse, both stimulate collagen production which is the disease process with these disorders. I'm not willing to risk the possibility of stimulating a medical problem to achieve a cosmetic improvement.

I would not be comfortable injecting Radiesse in a patient with a history of scleroderma. Restylane and Juvederm are hyaluronic acid fillers so they should be perfectly safe for superficial wrinkles. Stimulatory fillers such as Radiesse and Sculptra work by stimulating your skin to produce more collagen, which is why they are much more effective at treating problems due to volume loss. Since scleroderma is a disease that causes overproduction of collagen I would be concerned as to the safety... more