Meige's Syndrome treatment with Botox

I received Botox treatments for a neurological condition called Meige's Syndrome, which involves excessive facial twitches and blinking. After a treatment 4 1/2 months ago, I'm still experiencing weakness in my upper lip, and still unable to smile (not due to tightness but rather the inability to lift my upper lip upwards). The area below my nose down to my upper lip looks completely dead and sagging; pictures show this quite obviously, which is how I became aware of it. I thought the effects should wear off more quickly. Could something else be wrong? Please help, because I am only 36, and although the twitches are quite embarrassing, my inability to smile is very distressing also. Thank you for your help.

4 answers to “Meige's Syndrome treatment with Botox”

A: Botox Longevity

Steven H. Williams, MD

Thanks for your question - Botox can take up to six months to wear off.  Cranial dystonia (Miege's syndrome) can affect the muscles around the eyes in addition to those in the jaw, tongue and mouth.  Botox can be an effective way to block the involuntary contractions of these muscles. However, of... more

A: Botox can take 4 to 6 months to wear off.

David Shafer, MD

Depending on how you look at it, it is either fortunate or unfortunate that Botox takes 4 to 6 months to wear off. Do not worry about any permanent weakness caused by Botox. Botox always wears off. If you have already waited 4.5 months, then it may still take a month or so to wear off. Hang in there, it... more

A: Probably OK

Steven Wallach, MD

Botox effects can last from 4-6 months especially in patients that have had Botox before or have weaker muscle action. 

A: Longevity of Botox can be dose related

Robert M. Freund, MD

Dear Meige's sufferer, A patient's response to Botox is partly the result of muscle strength and Botox strength. The weaker a muscle is, the more profound the result of Botox. The stronger the concentration of Botox the better and longer the result. I use high doses of Botox in the frown areas and routinely... more

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