Photodynamic therapy vs. Efudex - which is better for treatment of actinic keratosis?

Photodynamic therapy vs. Efudex - which is better for treatment of actinic keratosis?

I've seen some horrible looking pics posted on the internet from patients that had horrific responses to treatment with FU-5 - they said the pain, oozing (sometimes bleeding) was almost more than they could stand for 2-4 wks. What is a ballpark cost for @ treatment - not sure if my insurance will pay for this but I need to do something about the AK's on my face and forearms - more extensive than than would be practical for cryosurgery - according to my Dermatologist.

3 answers to “Photodynamic therapy vs. Efudex -...”

A: Prefer PDT

Arnold R. Oppenheim, MD

     A recent article by Gold showed that after one year, photodynamic therapy led to a greater clearing of actinic keratoses than Efudex. It should be noted that this finding was applicable if the patient had two photodynamic treatments. Another recent study demonstrated that the use of Aldara... more

A: Chemoprevention of precancerous lesions and the concept of Preventive Dermatology

William Ting, MD

Several chemopreventive modalities to treat actinic keratoses and prevent skin cancer are available and should be aggressively pursued. An experienced board-certified dermatologist with keen interest in Preventive Dermatology and Chemoprevention can outline pros and cons of topical 5-flurouracil, imiquimod,... more

A: Treatment for AK's

Todd Minars, MD

Both methods are effective for the treatment of AK's but Efudex is the "gold standard". It is not easy to use, but you do not have to become one of those pictures you mention in your question. I have patients use Efudex until they get a response, meaning until they start to get a little... more

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Comments

Cheryl H.
2 posts
24 May 2009

A few years ago, I had PDT and saw great results. Less acne and smaller pores. I am now 30 and while I use Obagi NuDerm to control my acne, my t-zone has once again been suffering from large pores. Should I do PDT again because of my past success or is there something different to do since I now only have large pores to treat? Thank you.

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