Psoriasis is an autoimmune disease and I have read several posts on RealSelf where doctors have urged anyone with an autoimmune disease to steer clear of Sculptra (although the posts seem to refer to diseases such as Lupus, instead of Psoriasis). I current take Otezla and Meloxicam. My dermatologist is considering taking me off of the Otezla and starting me on an injectable biologics drug, such as Stelara. Any insight would be greatly appreciated.
Answer: Sculptra and autoimmune diseases Dear 42goingon35, this is a very interesting question and the short answer is that there have not yet been any large, well-controlled studies published in the academic literature addressing your specific concerns. Therefore, all we can do is hypothesize based on what we know of rheumatoid arthritis, psoriasis, and Sculptra. Rheumatoid arthritis and psoriasis are considered “autoinflammatory” conditions, meaning that patients with these conditions are more prone to develop inflammatory responses against their own bodies. Sculptra is a biostimulatory filler that functions by triggering a very small inflammatory response in the skin that eventually results in new collagen synthesis. Therefore, since Sculptra does trigger a very small inflammatory response, there may be a theoretical increased risk with its usage in the setting of a pre-existing autoinflammatory condition. Conversely, anti-inflammatory medications such as Stelara and Otezla are not likely to increase the risk but may decrease the efficacy of the treatment. All that being said, my opinion is that the risks with Sculptra will still be minimal and that you would likely still be able to enjoy this product, assuming that you are a good candidate for the treatment itself. Good luck!
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CONTACT NOW Answer: Sculptra and autoimmune diseases Dear 42goingon35, this is a very interesting question and the short answer is that there have not yet been any large, well-controlled studies published in the academic literature addressing your specific concerns. Therefore, all we can do is hypothesize based on what we know of rheumatoid arthritis, psoriasis, and Sculptra. Rheumatoid arthritis and psoriasis are considered “autoinflammatory” conditions, meaning that patients with these conditions are more prone to develop inflammatory responses against their own bodies. Sculptra is a biostimulatory filler that functions by triggering a very small inflammatory response in the skin that eventually results in new collagen synthesis. Therefore, since Sculptra does trigger a very small inflammatory response, there may be a theoretical increased risk with its usage in the setting of a pre-existing autoinflammatory condition. Conversely, anti-inflammatory medications such as Stelara and Otezla are not likely to increase the risk but may decrease the efficacy of the treatment. All that being said, my opinion is that the risks with Sculptra will still be minimal and that you would likely still be able to enjoy this product, assuming that you are a good candidate for the treatment itself. Good luck!
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CONTACT NOW Answer: Santa Monica Sculptra injections Sculptra injections can dramatically improve fine and deep wrinkles on the face. In my practice, I continue to see very positive results. Best, Dr. Karamanoukian Los Angeles
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CONTACT NOW Answer: Santa Monica Sculptra injections Sculptra injections can dramatically improve fine and deep wrinkles on the face. In my practice, I continue to see very positive results. Best, Dr. Karamanoukian Los Angeles
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November 10, 2015
Answer: Sculptra & Arthritis You definitely don't want to use sculptra if you are having a Psoriasis outbreak and frankly, it's probably not a good idea to use it with the arthritis. I would suggest that you speak with your surgeon about another filler that isn't collagen stimulating. Best, Dr. Nazarian
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CONTACT NOW November 10, 2015
Answer: Sculptra & Arthritis You definitely don't want to use sculptra if you are having a Psoriasis outbreak and frankly, it's probably not a good idea to use it with the arthritis. I would suggest that you speak with your surgeon about another filler that isn't collagen stimulating. Best, Dr. Nazarian
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October 28, 2015
Answer: Collagen Stimulators with Connective tissue disorders I do not use any collagen stimulating injectable in patients with any connective tissue disorder. Although there are virtually no reports or studies on the safety, it just doesn't make sense to do this. Hyaluronics are the only product I will use in such patients, and even here I just do not encourage high volumes to be used and ask these patients to keep a balanced perspective on what we are trying to achieve relative to their other medical conditions.
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CONTACT NOW October 28, 2015
Answer: Collagen Stimulators with Connective tissue disorders I do not use any collagen stimulating injectable in patients with any connective tissue disorder. Although there are virtually no reports or studies on the safety, it just doesn't make sense to do this. Hyaluronics are the only product I will use in such patients, and even here I just do not encourage high volumes to be used and ask these patients to keep a balanced perspective on what we are trying to achieve relative to their other medical conditions.
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October 21, 2015
Answer: Sculptra and Autoimmune Disorders There are no published studies stating whether Sculptra has any effect on autoimmune disorders. However, in my practice, I only treat patients that have autoimmune disorders with Hyaluronic acid fillers to be safe. Also, I ask my Sculptra patients to take caution with anti-inflammatory medications as it could interfere with the inflammatory process that Sculptra requires to be a successful treatment. Sculptra is an amazing treatment for pan-facial volumization for the right candidates. Meet with a Board Certified Plastic Surgeon to discuss your options further.
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CONTACT NOW October 21, 2015
Answer: Sculptra and Autoimmune Disorders There are no published studies stating whether Sculptra has any effect on autoimmune disorders. However, in my practice, I only treat patients that have autoimmune disorders with Hyaluronic acid fillers to be safe. Also, I ask my Sculptra patients to take caution with anti-inflammatory medications as it could interfere with the inflammatory process that Sculptra requires to be a successful treatment. Sculptra is an amazing treatment for pan-facial volumization for the right candidates. Meet with a Board Certified Plastic Surgeon to discuss your options further.
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