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Is Botox Appropriate for Nasolabial Lines?

My main concern are nasolabial lines. I've read about frown and brow lines; is Botox appropriate?

Doctor Answers 16

Botox is for the eyes and up

Dear Thesky

BOTOX works by weakening muscles. The muscles that pinch the brow are best treated with BOTOX. However from about the eyes down BOTOX can create problems with the muscles of facial expression and mouth movement. In particular, BOTOX has no role in treating the nasolabial fold.

Fillers are much better and safer treatment choices for the nasiolabial folds.

Los Angeles Oculoplastic Surgeon
5.0 out of 5 stars 20 reviews

Botox is not for nasolabial folds

Botox is not used for nasolabial lines. Generally it is not advised to weaken these muscles as it can create the appearance of a stroke..

Fillers are generally used for this purpose.

Otto Joseph Placik, MD
Chicago Plastic Surgeon
5.0 out of 5 stars 60 reviews

Botox is dangerous in the nasolabial lines.


Botox near the nasolabial lines can weaken the muscles that lift your upper lip and that enable you to smile.  And it doesn't work anyway.

These lines need to be filled with either Restylane or Juvederm.

George J. Beraka, MD (retired)
Manhattan Plastic Surgeon
5.0 out of 5 stars 9 reviews

Fillers best here

While a tiny touch of Botox in a muscle called the Levator Superioris Nasii might slightly soften a nasolabial fold, it will lenghten the upper lip and possibly cause other unwanted side effects like changing your smile, so I'd say NO.

Fillers do such an awesome job in this area, especially when combined with a little filler in the cheeks, there is no reason to do Botox here.

Mary P. Lupo, MD
New Orleans Dermatologist
5.0 out of 5 stars 12 reviews

Fillers Are Appropriate for Nasolabial Folds

Botox is generally used to soften wrinkles mainly between the brows, forehead, crows feet, and bunny lines. Fillers are more appropriate for correcting the deeper folds  at areas below the eyes. It is best to have a consultation with an experienced injector in order to determine what will best address your needs.

Fillers are better

Botox is good for wrinkles that appear when making facial expressions. Nasolabial folds are visible even when your face is neutral. In addition, if you had Botox administered here, it will negatively affect the movement of muscles you need for daily facial movement. For this reason, fillers are better for this area.

Fillers better than Botox for nasolabial folds

The best treatments for nasolabial folds are fillers.  Fillers are injectable substances that plump up the skin from below, reducing the depth and shadowing that occurs as nasolabial folds deepen.  I try not to completely eliminate the nasolabial folds because this begins to look un-natural.  With fillers I start slow and build up if the patient requests it.  In Austin my patients want to look better, but they don't want to look like they've had "something done".  Fillers I use include Juvederm, Restylane and Radiesse.

Daniel J. Ladd Jr., DO
Austin Dermatologist

Botox for Smile Lines

Hi Sky,

Botox is great for wrinkles caused by muscle contraction like the frown lines between the eyes and the crow's feet at the outer eyes. Muscle activity in these areas are responsible for the development of fine lines and wrinkles. Using Botox in these areas can halt the muscle contraction and therefore get rid of the wrinkles.

The smile lines (nasolabial folds) are caused by an altogether different problem. Gravity and loss of volume in the skin combine to cause the lines that appear between the sides of the nose and the corners of the mouth. In this area dermal fillers like Restylane, Juvederm and Perlane are a much more appropriate choice as they are designed to add volume.

Harold J. Kaplan, MD
Los Angeles Facial Plastic Surgeon
5.0 out of 5 stars 6 reviews

Botox and nasolabial folds

 Botox is not a good treatment for nasolabial folds.  The best thing to treat the deep nasolabial folds are filler products like restylane, juvederm, and radiesse.

Steven Wallach, MD
New York Plastic Surgeon
4.0 out of 5 stars 22 reviews


The folds you are referring to result from time, gravity, and a weaking of the mid-face structures moving forward and downward.  Botox works by weakening muscles that cause wrinkles.  Therefore, fillers would be more apporpriate, or even a mid-face lift.


These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.