Migraine, Nausea and Body Aches After Restylane Injections? Doctor Answers, Tips
Restylane: Q&A
Ask a Question

Migraine, Nausea and Body Aches After Restylane Injections?

Four months ago I had restylane injected in tear troughs with no side-effects. Last week, I had non-surgical rhinoplasty with restylane; the doctor used he remaining product to refill my tear troughs. I'm very happy with the aesthetic result. However, I've been feeling unwell since. The day after the injections I developed a migraine for the first time ever. Two days later I had muscle aches, nausea and headache which lingered for 4 days. Why is this? Should I avoid restylane in the future?

6 Doctor Answers | Asked by girl01979
+3

Flue like Symptoms After Restylane

Normally, I would have said you were having a flu that happened to be after your treatment. However 1 month ago I got an email from someone in England describing the same symptoms after Restylane. She is very allergic to things.Her symptoms took 3 to 4 weeks to go away.She is finally feeling better.I find it interesting that both of you are not in the US and wonder if it is the exact same product used around the world. I would go cautiously if you do more Restylane treatments... more
+1

Flu-like symptoms after Restylane treatment

It is great to hear that you were able to obtain a great result from your treatment. From what it sounds like, you are experiencing flu-like symptoms following your injections that are a pure coincidence. This is especially likely since you did not experience any side effects from the treatment in the past. Restylane, no matter where it is injected, should not cause the symptoms you describe. The typical side effects of Restylane may include minor bruising and swelling, redness,... more
+1

Migraine, nausea, and body aches following Restylane

Sorry to hear about your experience. It is likely that your flu-like symptoms are coincidental with the Restylane treatment. In general, the treatment would not result in a migraine. This is a specific issue that would need to be addressed separately. The typical side effects of Restylane may include: 1) Minor bruising and swelling 2) Infection 3) Hematoma 4) Redness 5) Irregularities due to poor technique Side effects specific to the use of... more

You might also like...

Real Stories

Restylane and Perlane - Vancouver, WA

I just recently had this done the first time 3 days ago. The only other filler i have had...

Before + After Photos

View 257 Restylane photos
+1

Flu-like symptoms are unrelated to Restylane

There is no correlation between your symptoms and injection of facial fillers. It is probably coincidental. Hope you are feeling better!
+1

Migraine, Nausea, Aches after Restylane

This sounds like you have some sort of viral, flu-like illness that occurred coincidentally after your Restylane treatment. Please see your internist if your symptoms persist.
+1

Restylane and feeling ill

From what you describe, it doesn't sound like complications from your recent Restylane injections. It sounds more like the flu! Always follow up with the provider if you have bruising, swelling, or pain that is severe to the areas injected.
Doctors will not see your comments on their answers. If you'd like to follow up, please go here to ask another question.

Comments (2)

MBAgirl 4 Mar 2013
I spoke to a pharmacist at Midicis Aesthetics about Restylane and Restylane-L.The only diff is the L contains Lidocaine. The ingredients are: Hyaluronic acid is generated by Strep bacteria (Restylane contains gram positive bacterial proteins) NOTE: "Hyaluronan (also called hyaluronic acid or hyaluronate or HA) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions.[2] One of the chief components of the extracellular matrix, hyaluronan contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors. The average 70 kg (154 lbs) person has roughly 15 grams of hyaluronan in the body, one-third of which is turned over (degraded and synthesized) every day.[3] Hyaluronic acid is also a component of the group A streptococcal extracellular capsule,[4] and is believed to play a role in virulence.[5][6]" Wiki *The Restylane L contains saline and lidocaine. Both products have the same adverse reactions, or as Medicis calls the reaction, allergic or hypersensitivity reactions, which are nausea and vomiting and headaches, and anaphylaxis (the only reactions that they state as know and expected). So basically what we are likely reacting to is either the Lidocaine or the Strep bacteria proteins, bcuz Hyaluronic acid is found in the body. The definition of a hypersensitivy reaction, which it is specified as the nausea, headaches, vomiting, according to Medicis/Restylane is: Reaction produced by the immune system, which includes allergies AND autoimmunity. It requires a pre-sensitized (immune) state of the host - So I am guessing this means since I had nausea right away with the injection, I was exposed in the past to one of the ingredients and was allergic to it before the injection, (Bacteria or lidocaine), OR that is what they want us to think...What if it causes an autoimmune disease, like gluten causes celiac disease? Consider getting allergy & antibody testing done for the gram positive strep bacteria and maybe lidocaine. FURTHER RESEARCH: The Hyauluronic Acid is chemically modified with unknown added ingredient-CHEMICAL SENSITIVIES? "Native hyaluronan has a relatively short half-life (shown in rabbits) so various manufacturing techniques have been deployed to extend the length of the chain and stabilise the molecule for its use in medical applications. The introduction of protein based cross-links, the introduction of free-radical scavenging molecules such as sorbitol [found in fruits], and minimal stabilisation of the HA chains through chemical agents [!!!] e.g. NASHA stabilisation are all techniques that have been used. Research Due to its high biocompatibility and its common presence in the extracellular matrix of tissues, hyaluronan is gaining popularity as a biomaterial scaffold in tissue engineering research. In particular, a number of research groups have found hyaluronan's properties for tissue engineering and regenerative medicine are significantly improved with crosslinking, producing a hydrogel. This added feature allows a researcher to form a desired shape, as well as to deliver therapeutic molecules, into a host. Hyaluronan can be crosslinked by attaching thiols (trade names: Extracel, HyStem), methacrylates, [PLASTICS] and tyramines (trade name: Corgel) [Tyramine intake has also been associated with MIGRAINE] Hyaluronan can also be crosslinked directly with formaldehyde [POISON] (trade name: Hylan-A) or with divinylsulfone (trade name: Hylan-B) [SYNTHETIC RUBBER]" Wiki
girl01979 6 Sep 2012
Thank you for your replies. I hope you are right. However I have a strong feeling it was related to the restylane because I had just had a bout of flu two weeks prior to the restylane, but my symptoms had completely resolved by the time I got the injections. Getting the flu twice in the same month seems rather unlikely. Also, my symptoms were like nothing I had ever felt before. I never get nauseous with the flu, and I'd never felt that kind of pounding headache before either. I actually thought I was having a stroke or something. Anyhow it's been a week now and I am 100% back to normal. I will be getting more restylane next year. However I will pass on any touch ups right now (doctor could inject more product next week if needed) because I cannot run the risk of feeling that awful again so soon.

Ask a Question

Welcome Back

Sign in with Facebook

Your information remains private and will not be posted without your permission.

Forgot your password?

Don't have an account? Create one now.

Join RealSelf

Join with Facebook

Your information remains private and will not be posted without your permission.

Please enter a valid email address
 Did you mean ?

By creating an account, you are indicating that you have read and accept the RealSelf Terms of Use.

Already a member? Sign In.

Retrieve your password

Enter your username or email address and we will send you a link to login.

Check your email

Check your email. We've sent you a link to reset your password.

Ok