Botox not effective - I am told I "metabolize" this too quickly

Hi Katherine,  Research studies have shown that even patients who have antibodies to Botox associated complexes circulating in their bloodstream can still respond to its effects. I'd actually try going to a different provider and trying Botox again. There are many factors that can affect the efficacy of Botox's effects and your provider may have diluted it too much, had it sitting on the shelf for too long, bought it from a source not directly from Allergan, or not used enough units on you.   Dysport and Xeomin are also options, but, I'd actually try switching providers at this point.  Hope this helps!Dr. Kiripolsky 

My only suggestion would be to try another doctor. Your issue is not unheard of, but bottom line, Myobloc isn't going to make a difference. However, a higher dosage of Botox may help. Consult with a different board certified plastic surgeon in your area to discuss. Good luck --

Hi Katherine.  In the last 10-15 years we have only seen 2 or 3 patients with your set of circumstances.  These patients were not getting short duration or an allergic type reaction, they were just not getting the same results as everyone else.  So, what you are describing is possible.The only way to know for sure is to go to a new provider and try a higher dose.  It should not matter if it is Botox, Dysport or Xeomin as long as the does is high enough.  We would not recommend Myobloc as we have used this on those patients as well and it did not make a difference.  Los Angeles Dysport before and after photos at the link below.