Can Long-term Retin-A Application on the Neck Cause Thyroid Nodules by Any Chance?

I've been a Retin-A user for almost 5 yrs. now. I love it and believe it's one of the best products for your skin that really delivers results. I am 50-yrs-old. I use Retin-A cream 0.1% on both my face+neck 3-4 nights a week. I'm wondering if there's ever been any connection between repeated rubbing of Retin-A on the neck + the development of benign thyroid nodules. I don't have thyroid disease/thyroid cancer. I was tested this summer. But I do have a lumpy thyroid. Experts--any ideas?