What Are the Long Term Effects of Using Hyaluronic Acid Fillers? Doctor Answers, Tips
Injectable Fillers: Q&A
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What Are the Long Term Effects of Using Hyaluronic Acid Fillers?

If hyaluronic acids (juvederm, restylane, radiesse) are injected to the cheeks / face for over 20 years or more, what are the possible side effects? Are there studies for the use of these fillers for that long to determine their safety in long-term use?

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hyaluronic acid long-term
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1 Doctor Answer | Asked by welrj
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Long Term Effects of Hyaluronic Acid Fillers

Before I discuss potential long term effects, I think its is appropriate to define what hyaluronic acid is. Hyaluronic acid is a substance that is found in our bodies in the intra-and extracellular matrix. It is form of antigen-free tissue glue, if you will. Therefore, hyaluronic acid is naturally broken down in the body without adverse effects. Hyaluronic acid has been used for years in cartaract surgery and was FDA approved for cosmetic use (Restylane) in 2004... more
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