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How Long Does Accutane Stay in Your System

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Isotretinoin Completely gone by 1 month

+1

Accutane (Isotretinoin) is considered completely gone from your system 30 days after your last dose.  Donating blood and pregnancy should be avoided until then.

Since the medicines 1/2 life (time it takes 1/2 of medicine to be cleared form your body) is 21 hours, the vast majority is cleared by 4 days.

Metairie Dermatologic Surgeon
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