Can Latisse Seep into Eyes While Sleeping?

Even when used as directed, there is still a chance of iris darkening with Latisse. In our experience, it doesn't seem to require the agent actually getting into the eye.

There is no evidence to suggest that Latisse will change your eye color. The eye is exposed to a very small amount of Latisse even when it is properly applied as directed to the upper eyelid margin using the supplied applicator. This has been demonstrated by applying a colored dye to the eyelid margin and watching its migration. Over two million prescriptions for Latisse have been filled with no confirmed reports of iris pigmentation issues. Side effects from the initial studies showed less... more

You ask a great question. The answer appears to be that even though Latisse is applied to the eyelashes, it may be possible for a small amount to get into the eyes -- which could rarely lead to darkening of the iris. However, the risk of this happening is very low. For example, you may know that Latisse is currently used for glaucoma. It is called Lumigan, and is given once a day. Lumigan is very effective at lowering eye pressure. However, even though glaucoma patients place a drop of... more