I have large brown spot on cheek and have rosacea in same area. Is there any treatment that will not affect my rosacea?

Various laser can work in both conditions.The q switched yag in the 1064 wavelength can work on the brown spot and the 532 wavelength can improve the appearance of rosacea. Other option include pulse dye laser or Ipl.

The type of treatment depends on  your skin type, if the brown spot is raised or flat, and the type of rosacea you have. Intense pulsed light/IPL is a good option for flat sunspots in the setting of vascular rosacea or broken blood vessels. The IPL procedure targets both pigment and redness in the skin. IPL can either be targeted to a specific area, or can be used as a pan-facial treatment. It can take up to 1-3 treatments depending on the amount of pigment and redness present. If the brown spot is raised you might need an alternative type of treatment. If you have broken skin or active acne lesions of rosacea in the area of the brown spot you may want to hold off on treatment until the rosacea is under better control. Light chemical peels can also be done to lighten brown spots however a series of light peels may be required. I would recommend being careful with over the counter anti-aging and skin brightening creams in the setting of rosacea- many formulations can be irritating and can aggravate the underlying rosacea. I would see your dermatologist to discuss how to better control your rosacea and what would be the best option for you.