Off label treatment with accolate

Michael C. Edwards, MD answers: Accolate for suspected capsular contracture?

I am now 7 weeks Breast augmentation post-op and was recently told by my plastic surgeon that I may have beginning signs of capsular contracture, due to the firmness of my implants. I am still very swollen and my doctor suspects that I may have inflammatory problems that may need to be checked by my general doctor. I am currently taking 400-800 i.u. Vitamin E and Fish oil in hopes for improved healing, as well as rigorous massage and compression exercises. Should I be taking Accolate now as well?

Michael C. Edwards, MD
9 months ago

It is early to determine that you have a capsular contracture but the things we do to try to decrease the incidence are massage, Vit E ( no real good clinical studies to support it), and some recommend therapeutic breast ultrasound. The use of the prostaglandin inhibitors Accolat or Singulair is also somewhat controversial. Accolate is a medication used in the treatment of asthma and can potentially cause problems with you liver. In the few times I have used it I have not seen a clinical response and I followed the liver function studies on a monthly basis. I would discuss these questions with your plastic surgeon. Best of luck.

Dr Edwards

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