Does Juvederm or Restylane Have Paraphenylenedia in It

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allergic

5 Doctor Answers | Asked by Boston4453 in Boston, MA

Doctor Answers (5)
Community Comments (0)

No

No it does not. You may be confusing paraphenylenediamine with BBDE or Butanediol Diglycidyl, which is a chemical that is used to enhance the cross-linking of the hyaluronic acid in Restylane and Juvederm. The two are not related. It sounds like you might be allergic to hair dyes, since people who are allergic to paraphenylenediamine usually are allergic to permanent hair dyes or the dyes in furs (forgive me PETA for even mentioning furs!). If you are significantly allergic to PPD... more

Arnold R. Oppenheim, MD

5 reviews

Virginia Beach Dermatologist

Juvederm and Restylane do not have paraphenylenediamine in them

This chemical is known to be a strong allergen in some patients, possibly sensitized to it in the past by hair dye and other chemical products. Neither Juvederm nor Restylane, whether with or without the anesthetic, distributed here in the United States has paraphenylenediamine in them. I have just checked with the medical offices with both Allergan and Medicis, the respective companies of Juvederm and Restylane, and they have checked their sources to confirm that this chemical is... more

Does Juvederm or Restylane Have Paraphenylenedia in It

After reading both packaged labels - NO it does not contain this chemical. From MIAMI Dr. Darryl J. Blinski

Paraphenylenediamine is a component of hair dye that can cause contact dermatitis

Paraphenylenediamine is a component of hair dye that is used in pretty much all dyes except bleached blond. It is essentially what gives hair color dyes blackness. Many dyes have it and a certain percentage of the population will develop an allergic contact dermatitis to it. Allergic contact dermatitis becomes more severe with exposure. So every time you have your hair colored, you body remembers it has an allergy to the hair dye and reacts faster and stronger... more

Not according to the manufactures

Paraphenylenedia is a dye that can cause dermatitis. However this compound is not found in the filler products. If you are experiencing an allergic type sensitivity to a filler, please report this to your doctor. Allergy to a filler product although rare has been reported and is possible even if in the past you have not had a reaction.