Is There a Risk of Alloderm Causing Infection?

I have been using AlloDerm for breast reconstruction for many years and although it hasn't been clinically proven that there is an increased possibility of infection, some patients are concerned about it. I have had great results with using it. With any type of surgery, there is a risk of infection. Go over the pro's and con's of doing the surgery with or without the AlloGraft with your surgeon and allow them to assist you with making the decision. more

Alloderm itself will not increase your risk for infection after surgery. However, if you do experience an infection, it might become necessary to remove the Alloderm to treat it. This is true of virtually all surgical implants, and if your surgeon thinks that Alloderm will improve your chances for a good result, then I would have no qualms about using it.

I have been using AlloDerm and breast reconstruction surgery for the last 5 years. Clinically I haven't noticed an increase in postmastectomy reconstruction surgeries using AlloDerm and tissue expanders or implants. I think most of my colleagues agree that AlloDerm does not cause an increased rate of infection. It is a product that has really improved the overall results of postmastectomy reconstruction is using implant products. It also is very useful in both aesthetic and... more

Alloderm is a unique product derived from donated skin with all of the cells removed, leaving the collagen matrix which serves as a template for your own tissue to regenerate. I have been using it for more than 10 years and have had a very good experience with it. Although it is not strictly sterile, there have been no reported instances of infection transmitted from the donor. There are other products that have been put through a sterilization process but they all damage the collagen... more

Alloderm is a tissue matrix that is processed to remove cells, as well as bacteria.  IThe collagen and elastin fibers remain and the body's own cells grow in to this matrix, incorporating it. t is always possible to have an infection, but not any more likely just due to the alloderm.

It is logical to be concerned regarding the risk of HIV, Hepatitis, or some other serious infection when Alloderm is implanted.  The processing of this human-derived material destroys these pathogens.  Essentially, there is no risk of transmissible illness.  However, alloderm is not your own native tissue.  Thus, though the risk is small, there is a slightly increased risk of infection following surgery with this substance.  There are newer materials... more

AlloDerm is a regenerative tissue matrix that is processed from human skin. In a special enzymatic process, cells such as skin cells, bacteria, and viruses are removed, leaving behind support structures, such as collagen, elastin and growth factors. There have been no proven cases of infection caused by AlloDerm.

There is no inherent risk of infection from Alloderm as a product. Alloderm is human dermis treated via a chemical process to remove the cells from the skin leaving the basic collagen framework. Included in this process is a wash with different antibiotics. Once placed into the body, it becomes rapidly incorporated. What this means is that your body will grow into the Alloderm and bring blood supply to it, eventually replacing it. This rapid ingrowth of blood vessels minimizes the risk... more

It is processed skin which goes through a rigorous process of identifying any infections or diseases like HIV, Hepatitis etc. It has been used extensively and has great track record. It is well tolerated and with time gets incorporated into your own tissues. Regards

Alloderm is derived from human dermis. However,the process removes all the cells and only leaves the fibrous framework,which allows regeneration from the tissues. I'm not aware of any reported infection related to alloderm usage and the chance of transmission of infection is very slim.  

Alloderm is highly processed and sterilized.  It is tested before shipping.  That said however, there is always a chance that there will be a breach in sterility. Alloderm should really pose no more of an infection risk than any other implantable medical device. sek