Latisse can often be safely used with topical creams.
But I would like to know much more about the cream you're using before combining the two. Is it a retinoid cream? A moisturizing cream? An anti-oxidant cream? Are you applying the cream to the upper lids? The lower lids?
Latisse is not contraindicated with any particular over the counter creams at this time, and can be used either before or after with safety.