Will I receive an initial breakout when I start Spriolactone for my hormonal acne? I have slightly elevated testosterone. My derm said no I won't. But I've read a ton of reviews and a bunch of women say they had a horrible breakout for 2 months! Why would it cause a breakout if it block androgens? I'm starting on 25mg twice a day.
Will I Receive an Initial Breakout from Sprinolactone?
Doctor Answers (1)
You are very unlikely to see an initial breakout from initiation of spironolactone therapy. Realize that with hormonal acne, you are dealing with a disease that has cyclical fluctuations, so there is certainly a possibility that you could have a cyclical flare before the spironolactone begins to benefit you, but the medication itself is not generally associated with a "worse before it gets better" phenomenon.