Hyaluronidase risks - potential side effects

You state that hyaluronidase can more rapidly break down fillers in face. Does it break down natural acids in face, too? Can it cause perminant holes or scars in face? Is it FDA approved?

3 answers to “Hyaluronidase risks - potential side...”

A: Hyaluronidase can break down bumps from Juvederm and Restylane

David Hansen, MD

Hyaluronidase is great at smoothing down bumps from Juvederm or Restylane but may take a few weekly injections and doesn't affect the normal skin at all so it has no permanent problems with regular use.

A: Hyaluronidase can rapidly reverse the effects of hyaluronic acid fillers

Scott Trimas, MD

Hyaluronidase can rapidly reverse the effects of hyaluronic acid fillers. It is a very safe product and I have been using it for 15 years. I also use hyaluronidase for dispersing the effects of local anesthesia when I do eyelid surgery and it works very well. When used in small doses, it can quickly within... more

A: Hyaluronidase is not FDA-approved

Ira D. Papel, MD

Hyaluronidase is an enzyme which accelerates the absorption of hyaluronic acid based dermal fillers. When used in small quantities it can help to smooth bumpy areas after cosmetic filler injection. When restricted to overfilled areas, the response can take a few days to be noticeable. It does not seem to cause... more

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