Can Hyaluronidase Help W/ Swelling 11 Months Post Sculptra Trtment Under Eyes? (photo)

47 yr old, model @ Sculptra RN training by plastic surgeon who wanted to inject along the lower orbital bone. I hesitate, is that appropriate since Sculptra is not indicated for use there. He reassured me, he has done this many times w/ good results. Swelling 11 mos post trtmnt. MD offers hyaluronidase-pocket of swelling seems to be "stuck" w/in tissue. 72 hours post trtmnt, swelling only slightly better. What if it doesn't completely resolve?

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6 Doctor Answers | Asked by AnMaCi

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Never allow anyone to inject Sculptra® into your face.

Never allow anyone to inject Sculptra® into your face. At one time it was considered an important agent in managing facial fat loss in HIV+ patients. Prior to FDA approval, it was used in a clandestine manner. In clinical trials evaluating this agent for correction of fat loss in HIV+ patients although the study patients were for the most part satisfied, up to 50% of the injected individuals developed some degree of lumpiness in the treated areas. Furthermore, these lumps are often far... more

No Hyaluronidase for Sculptra

Hyaluronidase only works to break down Hyaluronic acid type fillers (Juvederm, Restylane, Perlane) Sculptra is not a "filler" but a collegian stimulate so it will not be affected by Hyaluronidase.

Will hyaluronidase help sculptra bumps under the eyes?

No, they wont. Simply because Sculptra is not made from hyaluronic acid so there is no way that the enzyme is going to help. Sculptra nodules may be surgically removed (I published an article on this in Drugs in Dermatology) or they can be treated with injections of cortisone.

Sculptra cannot be removed with hyaluronidase

I am so sorry to hear about your experience. Hyaluronidase is a great option for the uncommon complication of hyaluronic acid fillers such as Restylane, Perlane and Juvederm. It will dissolve those products and return your facial contours to their normal pre-injection shape. However, Sculptra is a different product entirely and will not be dissolved by hyaluronidase. Rarely, Sculptra can result in nodules and these contour deformities can be surgically removed improving the appearance.... more

Swelling from Sculptra treatment

Now that you are 11 months post Sculptra treatment, what you see is no longer swelling but is your final result. The periorbital area is very tricky to inject because of the relatively small distance between the skin and the underlying bone. Since the collagen response from Sculptra treatments will vary from one person to another, treatment in this area is risky, even with an experienced injector. Sculptra is not a hyaluronic acid filler so hyaluronidase is unlikely to have much effect.... more

Hyaluronidase does not dissolve Sculptra

Hyaluronidase dissolves hyaluronic acid dermal fillers, like Juvederm, Restylane and Perlane. Sculptra is not really a filler. It is a biostimulator. It is composed of poly-L-lactic acid, a relative of sutures placed inside the skin when an excision is performed. It is also a relative of alpha hydroxy acids. Sculptra particles stimulate new collagen deposition around themselves. The only way to remove Sculptra particles is for the body to dissolve them... more