Hyaluronidase Should Dissolve Juvederm

Mark Berkowitz, MD answers: Can Hyaluronidase injections dissolve Juvederm several months later?

I had Juvederm injected in my laugh lines and under my eyes to fill out the hollows. It was too swollen and the doctor dissolved some of it with enzyme, but she did it unevenly, resulting in unnatural lumpiness and swelling that has still not decreased after 9 months! I am certain it is the product because I never had bags or swelling prior to this procedure. I also have lumps under my smile lines that now appear as jowls. Can these lumps still be dissolved by hyaluronidase injections?

Can Hyaluronidase injections dissolve Juvederm several months later?
Mark Berkowitz, MD
15 months ago

I am sorry to learn of the difficulty that you are experiencing. Perlane, Juvederm, Restylane or Elevess are all Hyaluronic Acids (HA). The beauty of them is that they are soft and work well to fill in lines and wrinkles around the face.

Side effects from these fillers and dissatisfaction is rare. When these occasions do occur the wonderful thing about this group of fillers is that we can offer Wydase or Hyaluronidase to reduce or dissolve them.

As an Ocular Plastic surgeon, in the suburbs of Detroit, I utlize Wydase all of the time as part of my freezing solution for eyelid surgery. Side effects from this substance are rare with the most common being an allergic reaction (which I personally have never encountered with over 3000 procedures, Knock wood:))

I would ask you to return to your trusted physician to see if he would use the hyaluronidase to reduce this lower eyelid lump. You cauld also consult an Ocular Plastic Surgeon who could surgically remove the filler.

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