I don't think platelet rich plasma or PRP injection for "eye wrinkles" is the best treatment. There are several types of "eye wrinkles". There are wrinkles that appear around the eyes when the eye is constricted and these are called dynamic wrinkles. These sometimes can be best treated with Botox around the lateral portion of the eye. If the problem is excess lower eyelid skin or wrinkles, the solution maybe a chemical peel, laser, or a lower eyelid lift or blepharoplasty. If there is a significant hollowing of the lower eyelid, a filler maybe needed such as fat or reJuvéderm.
How Effective is Autologous Platelet Transfer for Eye Wrinkles?
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PRP and Fat Transfer
PRP and fat Transfer may be better than either one. This is just conjecture, but the growth factors in PRP may help the fat to establish itself. It may also help the stem cells work in those areas as well.
Autologous platelet transfer is not effective for eye wrinkles
Here in Miami, we have seen many patients who have received platelet transfer to the eye region for the correction of wrinkles. Unfortunately, they have come to our office because these procedures did not work and they are looking for a more effective solution. At this time, the most effective solution for the crows feet, is a small application of Botox. Wrinkles in the upper and lower eyelids, may be treated with peels, laser, or a blepharoplasty. When considering treatment around the eyes, keep in mind that is a very sensitive area and so it is essential to work with the plastic surgeon who is extremely experienced and blepharoplasty, fillers, and Botox. Such a surgeon will be able to determine which combination of these techniques will help you meet your goals.
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Here is an excerpt from an article... you decide.
"Regarding facial rejuvenation and PRP, initial results are short-lived, inconsistent and further maintenance treatment is needed regarding facial wrinkle amelioration, as is the case with other fillers. It is not clear if "neocollagenesis" occurs after PRP rejuvenation therapy. Drawbacks of activated PRP, if used in the facial area, include the potential to micro-thrombosis in the region of the anterior facial vein, closed compartment syndrome and release of pro-inflammatory proteolytic activators from leucocytes."
Sounds iffy to me in a purely wrinkle treatment role.
Stick with FDA approved fillers for wrinkles
In regards to facial rejuvenation, platelet rich plasma is experimental. Although it has been shown to help improve some wrinkles, it is associated with significant complications with micro thrombosis (clotting) of the anterior facial vein and compartment syndrome and release of pro-inflammatory proteolytic activators from leucocytes. So, stick with your FDA approved fillers. Leave this stuff for the orthopedists and cardiovascular surgeons like myself who have used it to help heal torn achilles tendons, to help heal infected sternal wounds, and help heal stubborn ulcers in the lower extremities.