Breast Augmentation Q&A
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Can Graft Versus Host Disease Complicated Breast Augmentation Surgery?
asked 1 year ago by toriedrn in Providence, RI
Latest answer by George Sanders, MD
Question viewed 230 times
Tags: female, medical history
S/P Stem cell transplant 2003. looking to have breat augmentation. Still have cGVHD and am on 5 mg prednisone and 1 mg sirolimus. Can my history complicate breast augmentation beyond the usual risks?
8 answers to Can Graft Versus Host Disease Complicated Breast Augmentation Surgery?
+1
Breast Augmentation and Graft versus Host Disease
Thanks for the question.
While a breast implant is in theory "inert" and shouldn't elicit an atypical immune response, given your history of immunosuppression and corticosteroid use, you are at higher risk for infection than the typical patient population. You must be cleared by your managing physician before considering an elective cosmetic procedure such as a breast augmentation.
Warmest Regards,
Glenn Vallecillos, M.D., F.A.C.S.
+1
Don't do it!
In a word, "Yes." Normal healing depends upon the body's inflammatory response and the drugs which you are on will not allow for a normal inflammatory response. I would discuss this issue with your oncologist. I suspect that he/she Will recommend against the breast augmentation as well.
George Sanders, MD
Los Angeles Plastic Surgeon
Los Angeles Plastic Surgeon
+1
Breast Augmentation vs GraftvsHost Disease
I would be very hesitant to perform breast augmentation under these circumstances. Your risk for complications would be significantly increased, especially for wound healing problems and infection. I would think the risks of breast surgery outweigh the benefits.
David H. Bauer, MD
Little Rock Plastic Surgeon
Little Rock Plastic Surgeon
+1
Breast implants and immune compromise
If you currently have graft vs. host disease you should not have any elective cosmetic procedure much less have implants placed to make your breasts bigger. Between the prednisone and the graft trying to destroy your own native tissue the risk for infection and wound problems is sky high. Everything needs to settle down for at least a few months before you could undergo any elective cosmetic surgery. If you develop any infection due to immune system compromise you should not have any...
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Aaron Stone, MD
Los Angeles Plastic Surgeon
Los Angeles Plastic Surgeon
+1
Immunosuppression and breast implant augmentation surgery
Steroids are immunosuppressants and may effect immunomodulators which can result in an increased risk of wound healing problems and infection.
Otto Joseph Placik, MD
Chicago Plastic Surgeon
Chicago Plastic Surgeon
+1
Breast Augmentation and GVHD?
Very good question. Unfortunately, there is very little information in the medical literature to answer your question. And while breast implants are considered to be inert, the biggest issue you may encounter is delayed healing due to your use of prednisone.
Your best best would be to speak with a Board Certified Plastic Surgeon in your area. Discuss your goals as well as concerns and see if he/she feels that you would be a good candidate.
I hope that helps!...
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+1
Transplant patients and breast implants
While there are no any studies looking specifically at transplant patients who have breast implants, from what we know about medical implants in general, they seem to be well tolerated. The biggest issue may be healing problems if you are on high doses of immun-suppressing medications. This can be discussed with your transplant doctor to make sure you are on an appropriate dose before surgery. As for GVHD, it is unlikely that this would result from a breast implant. From the best data we...
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Karol A. Gutowski, MD
Chicago Plastic Surgeon
Chicago Plastic Surgeon
+1
Breast implants do NOT elicit an immune response as a foreign organ
Regarding: "Can Graft Versus Host Disease Complicated Breast Augmentation Surgery?
S/P Stem cell transplant 2003. looking to have breat augmentation. Still have cGVHD and am on 5 mg prednisone and 1 mg sirolimus. Can my history complicate breast augmentation beyond the usual risks?"
For the benefit of the non-medical readers, when a graft or organ is taken from one human and placed in another, the recipient's immune system immediately is able to detect the graft is...
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