Which Wrinkle Filler Lasts the Longest?

Just because something lasts a longer time does not make it a better filler. It is my opinion that the longevity of the filling effects of Restylane and Juvederm in the nasolabial area are comparable. Both can last on the order of a year if you were initially treated with enough of the filler. I have the sense that Restylane will hold better in this area creating a more satisfying long term result. However, other injecting physicians may have the opposite opinion. I think that Perlane... more

Eveyone metabolizes the various fillers at different rates so there are no absolute answers to your question. Generally speaking, if we are talking about filler for the nasolabial folds, Radiesse is likely to give you the most durable effect - a smaller proportion of the filler is reabsorbed at 1 year when compared to the hyaluronic acid fillers (all the others in your list). As already mentioned, the drawback with Radiesse is if there are lumps or you dislike the result, the only thing... more