Which wrinkle filler lasts the longest?

There are so many line filler products: Radiesse, Perlayne, Restylane, Juvederm Ultra; which do you recommend for long-lasting results? My main area of concern are the nasolabial folds.

2 answers to “Which wrinkle filler lasts the longest?”

A: Lasting wrinkle fillers

Bryan K. Chen, MD

Eveyone metabolizes the various fillers at different rates so there are no absolute answers to your question.  Generally speaking, if we are talking about filler for the nasolabial folds, Radiesse is likely to give you the most durable effect - a smaller proportion of the filler is... more

A: many different perspectives on wrinkle fillers

Kenneth D. Steinsapir, MD

Just because something lasts a longer time does not make it a better filler. It is my opinion that the longevity of the filling effects of Restylane and Juvederm in the nasolabial area are comparable.  Both can last on the order of a year if you were initially treated with enough of the filler.  I... more

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