Artefill Under Eye Filler Reaction?

I've had Restylane and Artefill under the eyes. Restylane over a period of years; Artefill the 1st time two months ago after skin test w/ no reaction whatsoever. Within last couple of weeks I've had swelling under the eyes, which I can't connect to anything topical/ ingested. Medical history includes ideopathic hives several times, one anaphylactic reaction to sulfa/ sulphates, and other less pronounced reactions to sulfa/sulphates, asthma. Possibly Artefill related? I'm taking Benadryl.

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2 Doctor Answers | Asked by 5321anon in Concord

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Artefill under the eye is not FDA approved

Artefill under the eye is not FDA approved and is an off-label use of the product. You can have allergies to the Artefill even if you were tested. Swelling under the eyes often results, which is true with any filler. But, you can be allergic to the collagen under the eyes from the Artefill, even if you’ve been tested.

Artefill under eyes filler reaction

Has it gotten better or worse or stayed the same during the 2 weeks? If it is staying the same or getting better, I would wait a few more weeks. Even though the skin test was negative, you may have a reaction to the collagen portion of the Artefill. In this case, the swelling will most likely go down slowly. If after 4-6 weeks it is not getting better or if itgets worse, I would see a cosmetic dermatologist for a 2.5 mm punch biopsy which may clarify the type of... more