How is Evolence different from Restylane or Juvederm injections?

How is this new filler Evolence different from the HA fillers we know and love, i.e. Restylane or Juvederm?

Sort: Date | Helpful

8 answers to “How is Evolence different from...”

A: How Evolence differ from the other fillers

By Ritu Saini, MD - New York City Dermatologist

Evolence is a porcine (pig) collagen-based filler. Unlike the first generation collagen fillers, Zyplast and Zyderm which are bovine (cow) derived, skin test is not required. There tends to be less swelling associated with Evolence, as compared to some of the hyaluronic... more

A: evolence is collagen, restylane/juvederm are hyaluronic acid

By Jonathan Hoenig, MD - Beverly Hills Oculoplastic surgeon

Unlike Restylane and Juvederm which are made from hyaluronic acid, Evolence is made from collagen and that collagen is derived from pigs. Pig (porcine) collagen has been used for many, many years as an injectable filler as the collagen found in pigs is very similar to that of humans. That said, some people... more

A: Caution with Evolence in the Lips

By Brett S. Kotlus MD, MS - Michigan Oculoplastic surgeon

Evolence is a porcine collagen-derived filler initially released in Europe and Canada. It has a relative called Evolence Breeze which is a different version of the same substance (which has "a more finely textured consistency" according to the manufacturer, but they do not clearly describe how this... more

A: Evolence is a new collagen product

By Manish H. Shah, MD - Denver Plastic Surgeon

I have to say that my initial experiences with Evolence have been remarkable. I tell my patients that it is the event filler. Collagen is hemostatic which to you means minimal bruising. I have seen little post-injection redness. Per cc injected, I feel that my overall corrections are much more accurate. It... more

A: Evolence is Collagen based

By Kamran Jafri, MD - New York City Facial Plastic Surgeon

So what's so new & exciting about Evolence? Evolence is a collagen based filler which is used to correct moderate to deep facial wrinkles (most commonly the nasolabial folds). Unlike other fillers composed of hyaluronic acids (Restylane, Juvederm), Evolence utilizes a specially formulated GLYMATRIX... more

A: Evolence is a long lasting collagen filler

By Steven F. Weiner, MD - Fort Walton Facial Plastic Surgeon

Evolence is the latest Dermal Filler to be FDA approved. Of all the fillers, it is the most natural, and causes the least swelling and bruising. It is a collagen based filler but overcomes the hurdles that prior collagen fillers had. There is no need for pretesting to see if you have an allergy to it. Also,... more

A: Evolence is made of protein from pig collagen. Restylane...

By Ronald Shelton, MD - Manhattan Dermatologic surgeon

Evolence is made of protein from pig collagen. Restylane and Juvederm are laboratory synthesized hyaluronic acids which are found in the normal skin's infrastructure. There may be more bruising with the hyaluronic acids than Evolence.

A: Evolence is a cross linked collagen. HA, or hyaluronic...

By D.J. Verret, MD - Dallas Facial Plastic Surgeon

Evolence is a cross linked collagen. HA, or hyaluronic acid, which is the primary ingredient in Juvederm and Restylane, are a different compound and most of the effect of the substance in facial filler applications is due to water absorption from surrounding tissues. Johnson & Johnson (the maker of... more

Comments

Dr. Sachit Shah
52 posts
7 Jun 2008

Juvederm & Restylane Juvederm and Restylane are hylauronic acid-based fillers. They last at the most 6 months in the skin and require repeated filling. Evolence Evolence is a filler that is collagen-based and cross-linked with D-ribose. It lasts longer than the Restylane and Juvederm. I tend to find that the Evolence gives a much more natural and a longer lasting fill. In some patients, I have seen the hylauronic acid fillers last only 3 months in the lips, and the Evolence generally gives longevity. Also the costs for the Evolence are roughly the same as hylauronic acid fillers, so this works in the patient's favour.

Michael Sinclair MD
138 posts
25 Sep 2008

As has been stated before, Evolence is made out of Collagen, not Hyaluronic Acid. It is made in Isreal out of the achilles tendons of pigs. The material is altered with enzymes to make it nearly identical to human collagen. So far, there has not been even 1 case report of an allergic reaction to this product, so no skin testing is required! It probably lasts longer (about 1 year), it causes less bruising and very little swelling. All of this is good news! BUT....since it is made out collagen, I don't think there are any approved chemicals to dissolve it. If you go to an inexperienced injector, and you get a bump, you are probably going to have to live with it until it dissolves. This is no different than using Radiesse, and I use Radiesse all the time with great results, so I don't think this is going to be a major problem. Michael J. Sinclair, MD www.epilution.com

Post your question

Email to friend