How is Evolence Different from Restylane or Juvederm Injections? Doctor Answers, Tips
Evolence: Q&A
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How is Evolence Different from Restylane or Juvederm Injections?

How is this new filler Evolence different from the HA fillers we know and love, i.e. Restylane or Juvederm?

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11 Doctor Answers | Asked by anon
+4

Evolence is a cross linked collagen. HA, or hyaluronic...

Evolence is a cross linked collagen. HA, or hyaluronic acid, which is the primary ingredient in Juvederm and Restylane, are a different co mpound and most of the effect of the substance in facial filler applications is due to water absorption from surrounding tissues. Johnson & Johnson (the maker of Evolence) obtained FDA approval to market the compound in the United States on June 30, 2008. They have indicated that it will be available as soon as they can train physicians in its... more
+3

Evolence is a long lasting collagen filler

Evolence is the latest Dermal Filler to be FDA approved. Of all the fillers, it is the most natural, and causes the least swelling and bruising. It is a collagen based filler but overcomes the hurdles that prior collagen fillers had. There is no need for pretesting to see if you have an allergy to it. Also, while prior collagen fillers had a very short duration of about 2-3 months, Evolence is approved as a 6 month duration filler, but in studies it has been shown to have up to a 12 month... more
+2

Evolence vs Restylane vs Juvederm

Restylane and Juvederm have become the work horses of the injectable filler market. These hyaluronic acid fillers are derived from genetically engineered tissues and are thus safe and reliable. Evolence is derived from porcine collagen. Pig DNA is very close to human DNA hence the reason we use it for heart valves and the like. Unlike the older collagens that were made from beef and caused allergic reactions, Evolence doesn't require skin testing and isn't known to cause allergic... more

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+2

Evolence is Collagen based

So what's so new & exciting about Evolence? Evolence is a collagen based filler which is used to correct moderate to deep facial wrinkles (most commonly the nasolabial folds).Unlike other fillers composed of hyaluronic acids (Restylane, Juvederm), Evolence utilizes a specially formulated GLYMATRIX collagen which slowly integrates with the Patient's tissue. Unique to this collagen based filler is that no skin testing is required. This is because the proteins in the collagen that... more
+2

Evolence is made of protein from pig collagen. Restylane...

Evolence is made of protein from pig collagen. Restylane and Juvederm are laboratory synthesized hyaluronic acids which are found in the normal skin's infrastructure. There may be more bruising with the hyaluronic acids than Evolence.
+1

Evolence Collagen Filler

Evolence is a new dermal filler made of natural collagen, that has been naturally cross-linked to mimic the natural structure of the body’s own collagen. As a result, Evolence is able to integrate and support existing collagen by adding structure, strength, and volume for a natural appearing, long lasting result. Evolence is indicated in patients with moderate to deep facial wrinkles and folds, such as nasolabial folds, along with areas that require lifting such as the corners of the... more
+1

Difference between Evolence and Restylane or Juvederm

Your question has been expertly answered by the previous doctors so well. Down to the biochemical physiologic levels. But the real difference is the company has 'pulled' it from the market. This was stated due to poor sales. I think it was a total failure from its' marketing to its name choice. So why would you use a product taken off the market and not available? I would not. That is the real difference. PS: Artefill is now back on the market. Lasts 5 to 7 years. Only a few doctors will... more
+1

How Evolence differ from the other fillers

Evolence is a porcine (pig) collagen-based filler. Unlike the first generation collagen fillers, Zyplast and Zyderm which are bovine (cow) derived, skin test is not required. There tends to be less swelling associated with Evolence, as compared to some of the hyaluronic acid fillers Restylane and Juvederm. Therefore, the correction one gets with Evolence is typically exactly the same as immediately post-injection- what you see is what you get. Unlike the the hyaluronic acid based... more
+1

Evolence is collagen, restylane/juvederm are hyaluronic acid

Unlike Restylane and Juvederm which are made from hyaluronic acid, Evolence is made from collagen and that collagen is derived from pigs. Pig (porcine) collagen has been used for many, many years as an injectable filler as the collagen found in pigs is very similar to that of humans. That said, some people prefer not to use an animal based product for religious (muslim or jewish) or ideological (vegetarian or animal-rights) reasons. The advantage to Evolence is that the price may be lower... more
+1

Caution with Evolence in the Lips

Evolence is a porcine collagen-derived filler initially released in Europe and Canada. It has a relative called Evolence Breeze which is a different version of the same substance (which has "a more finely textured consistency" according to the manufacturer, but they do not clearly describe how this is achieved). A recently published case report from an experienced Canadian injector revealed a high incidence of nodules lasting over one year after injection. Therefore, its use in... more
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