Evolence Vs. Restylane, Which is Better?

Evolence is a porcine (Pig) derived collagen product used to provide soft tissue augmentation. Although no allergic reactions have been reported with Evolence, there have been several reports of nodule formation in the lips. In my Raleigh, North Cariolina Plastic Surgery we do not use Evolence. I am more comfortable using Juvederm, Ultra, Juvederm Ultra PLus Restylane, Perlane or Prevelle Silk as a temporary filler and fat grafting for individuals seeking permanent results.... more

Evolence is a dermal filler that replaces lost collagen in the face with natural collagen that is clinically proven to last at least 6 months. However, studies in Europe have shown this product to last about 12 months. The FDA approved Evolence in the United Stated in June, 2008. Evolence is recommended for the correction of moderate to deep facial wrinkles and folds, such as the nasiolabial folds (smile lines), and boasts immediate results with minimal-to-no bleeding, swelling, or... more

Evolence has recently been approved in the United States but has been in use in Europe since 2004. As far as pain, there is no evidence to a difference between Evolence and Restylane. There is a study recently published in Dermatologic Surgery which shows that Evolence lasts at least as long as Restylane to 6 months. In addition, the maker of Evolence has received approval to say that it can last 6 months up to a year; Restylane can only say it lasts up to 6 months.