Is Evolence Better Than Juvederm?

Evolence is a porcine (Pig) derived collagen product used to provide soft tissue augmentation. Although no allergic reactions have been reported with Evolence, there have been several reports of nodule formation in the lips. In my Raleigh, North Carolina Plastic surgery practice we do NOT use Evolence. I am more comfortable using Juvederm, Restylane, perlane or Prevelle Silk as a temporary filler and fat grafting for individuals seeking permanent results.

You know, it's always interesting to see what claims a company makes about the longevity of their injectable fillers versus what patients actually report to us. Evolence is being touted as lasting longer than previous collagens such as Zyplast and Cosmoplast (Cosmoplast is human collagen). The claims are that it lasts up to 12 months. The package insert only shows 6-month data showing that Evolence is no worse than Restylane. Indeed, there is a recent study in the medical literature from... more

Evolence is a collagen filler that has been shown in studies to last up to 12 months. It's an alternative to Juvederm, not necessarily better. It has been promoted as being a more natural filler, and if that's important to you, then you can switch. I have been cautioned by the company to not use it in the lips because it can cause nodules. However, Evolence Breeze will be able to enhance the lips when it is FDA approved in about a year. It has also been shown to have less bruising and... more

Evolence is a collagen filler which has been shown to last 12 months (recent data) and is most commonly used for correction of nasolabial folds. Juvederm is a hyaluronic acid filler which has a gel consistency and can be used for correction. The differences in consistency can be appreciated in the skin after injection. Evolence has a thicker consistency compared with Juvederm and may cause less bruising in nasolabial fold injections. Juvederm Ultra Plus is thicker than Juvederm and can be... more

Injecting Evolence seems to give a more even flow when I have been injecting it. The company states that it provides more of a scaffolding effect. This seems logical since collagen is a support structure for the dermis with hyaluronic filling the other spaces. One patient developed temporary erythema (redness) but this resolved after a few days. So far my patients seem happy with Evolence, but I am not sure whether they would have been just as happy with Juvederm or Restylane. I... more