Dysport work for a Botox-resistant patient?

My grandmother has built up a strong resistance to Botox through years of injections for treatment of cervical dystonia. She no longer sees a response to the injections, and she has been advised to give her body two years to degrade the immunity. Is Dysport different enough that she might respond?

4 answers to “Dysport work for a Botox-resistant...”

A: Resistance to Botox

Raffy Karamanoukian, MD

There are many patients who present to a plastic surgeon's office complaining that they need more and more Botox with continued use. It is completely feasible and theoretically possible that these patients should benefit from Dysport or Myobloc. 

A: Try Myobloc

John P. Di Saia, MD

Hello, Some patients who are resistant to Botox A (Botox) seem to respond to Botox B (Myobloc). Myobloc is FDA approved and I have found it safe and effective in my practice over the last three years.

A: True Botox resistance is very uncommon

Brian Biesman, MD

It may. While there may be a number of reasons someone may have achieved an unsatisfactory response to Botox, true Botox resistance is very uncommon. It is best to consult with a qualified physician to determine which of the botulinum toxin products would be most likely to produce optimal results. Review... more

A: Myobloc a Better Choice

Arnold R. Oppenheim, MD

    Botox, Dysport and Myobloc are all produced from the bacteria Clostridium Botulinum, the bacteria causing deadly botulism  (  Bon Vivant vichyssoise soup 1971 contained this). These neurotoxins  were originally isolated in 1946 at Fort Detrick in Frederick Maryland ( Camp... more

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