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173 reviews
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Dysport Work for a Botox-resistant Patient?
My grandmother has built up a strong resistance to Botox through years of injections for treatment of cervical dystonia. She no longer sees a response to the injections, and she has been advised to give her body two years to degrade the immunity. Is Dysport different enough that she might respond?
Asked 32 months ago by
cervicaldystonia2009 in Lexington, KY
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I have patients that respond well to Dysport that Botox did not work well
I personally have had patients who responded well to an equivalent dose of dysport when botox did not work well after a while for essential blepharospasm. The compounds are similar but not exactly the same. It is hard to determine why the dysport at the same corresponding dosage would work when botox would not but I have a multiple of patients who have had that response.
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Make sure adequate Botox or Dysport get injected for man or older woman
Most of the time when a man or an older woman does not respond well to Botox, it's typically a matter of not enough Botox units got injected to the desirable areas. True resistance to Botox is exceedingly rare. I do have patients for whom Dysport may work a little better than Botox and vice versa. Myobloc may work better but not yet FDA approved for cosmetic usage.
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Using Dysport in patients who have previously used Botox
Dysport is a close relative of Botox that is now available in the United States through Medicis. We have seen great results in patients who have previously used Botox or have developed a resistance, or in patients new to these muscle relaxers. If you have use Botox but have not been satisfied with the results, you may consider using Dysport and you may consider a stronger concentration of Dysport as you may have stronger muscles in this area. The amount of Dysport used is slightly...
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Dysport may work when Botox doesn't
Dysport and Botox are both Botulinum Toxin type A products. They are, however, subtly different. It is this small difference that may account for Dysport working where Botox does not. In my practice I have treated a couple of patients that don't respond to Botox injections. They seem to be doing well with Dysport so far. Traditionally we have used Myoblock for these patients, but Dysport presents another options. I would recommend trying Dysport if you find that Botox is not effective....
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True Botox resistance is very uncommon
It may. While there may be a number of reasons someone may have achieved an unsatisfactory response to Botox, true Botox resistance is very uncommon.
It is best to consult with a qualified physician to determine which of the botulinum toxin products would be most likely to produce optimal results.
Review of medical records that indicate the dose and placement of previous botulinum toxin injections can help determine how to achieve improvement with subsequent treatments....
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Myobloc a Better Choice
Botox, Dysport and Myobloc are all produced from the bacteria Clostridium Botulinum, the bacteria causing deadly botulism ( Bon Vivant vichyssoise soup 1971 contained this). These neurotoxins were originally isolated in 1946 at Fort Detrick in Frederick Maryland ( Camp Detrick back then) to be used as bacterialogical warfare.
Clostridium Botulinum produces seven distinct neurotoxins that are all neuromuscular paralyzing agents. The toxins are called botulinum toxin type A,B,C1,D,E,F...
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