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Does a Vial of Botox Come Pre-mixed?
I have heard Botox has to be mixed each time it is used. Is this true, or does it come pre-mixed? Thanks.
Asked 37 months ago by
apeeling one in Winnipeg, Canada
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Botox does not come pre-mixed
Botox does not come pre-mixed. Botox comes in a powder form and is shipped in a small glass vial. It is then mixed with Saline before use. It does not have to be mixed each time it is used, but 100 Botox units are mixed at a time.
Our patients normally have between 20 units and 60 units injected so in many cases a portion of the vial remains for the subsequent patients.
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Botox comes as a powder and needs to be reconstituted.
Each vial of Botox needs to be prepared for injection by adding fluid. Different offices use different dilutions, all of which are potentially valid. There are pros and cons for using different dilutions, but the key is really how many UNITS are being injected into an area, not how many cc's or vials. See a well-reputed board certified dermatologist or plastic surgeon, and make sure you feel comfortable and know exactly what you are paying for.
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Botox does not come pre-mixed
As answered by my colleagues before me, Botox comes as dried powder that must be kept refrigerated. The vial contains either 50 or 100 units. It is reconstituted in normal saline prior to your treatment. There is no set volume of saline that is used. It is up to the individual provider. It ranges from 1-6 milliliters(cc). I personally use 2 mls based on my own personal experience, and after talking with many of the experts here in the US and in other countries.
With that being said, it is...
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Botox bottles do not come premixed
Botox is a powerful and effective medication used to relax muscles and alleviate the wrinkles caused by them. Botox comes to the doctor's office as a frozen powder in an empty bottle. Your doctor will then add a small amount of saline water to the Botox to help resuspend it. This mixture is what the doctor will inject into your treatment areas.
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Botox comes in a concentrated powder
Every vial of Botox gets diluted when it is used. Doctors may use different amounts of saline to dilute the powder, resulting in Botox that is more or less concentrated. Depending on the areas being treated, one vial may be enough for 3 patients or it may only be enough for one patient.
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Botox does not come pre mixed
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Botox--Injector Picks Dilution
Botox does not come premixed. It comes freeze dried (kinda like astronaut food). The injector will help pick the dilution of botox depending on the intended application. Once botox is mixed it should ideally be used within 4 hours of reconstitution but this number is controversial. Botox can be made more dilute but can never be made more concentrated (Add saline to product but do not add actually botox to reconstitution).
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Botox does not come pre-mixed.
Botox does not come pre-mixed and needs to be reconstituted with normal saline prior to injection. Once mixed, the effectiveness of Botox can last for a certain period of time. Everyone dilutes their Botox with different amounts of normal saline, thus you should know how many 'units' of Botox that you are receiving and not how many 'cc's'. Good luck.
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No, it does not come premixed in liquid.
Botox Cosmetic does NOT come premixed in liquid. It comes as an extremely small amount of powder in a vial that is 'lyophilized', which is a fancy term for 'freeze dried". Botox cosmetic is measured in units. Units are a way of measuring the acrtivity, so all vials will have the same amountof activity, they all have 100 units. The powder can be dissolved with pure sterile saline. The amount of saline used to reconstitute the powder vaires on physician preference, but, in general...
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Botox Cosmetic by Allergan is available in a 100 unit multi-dose vial for injection of wrinkles
Botox cosmetic is manufactured by Allergan. This is the same company that manufactures Natrelle breast implants.
Botox is available in the United States in two different packages: Botox Serotype A for cosmetic use and Botox Serotype A for medical use.
Only Botox cosmetic should be used by your physician for the treatment of wrinkles. This is available in a multi-use vial containing a powder of 100 units of Botulinum Serotype A.
In my plastic surgery practice, I constitute the 100 units...
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It does not come pre-mixed
Botox cosmetic comes as a purified protein - not in suspension. It is reconstituted with some amount of saline - depending on the provider. After it is reconstitued, it should be used within 4 hours - according to the most stringent recommendations. Studies have shown, and it is our experience, that it retains its efficacy far longer than that. I hope this helps!
Dr. Kaufman
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Botox needs to be reconstituted
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