Does Botox for Hyperhidrosis Work?

I've heard that you can get Botox for hyperhidrosis (i.e. Botox for excessive sweating). Is this experimental or is it FDA-approved? Does it work?

Doctor Answers 46

Sweating - Botox is a safe treatment

Excessive sweating makes many a people self-conscious. A single Botox treatment can give back self-confidence for aprox. 5 - 10 months.  

Mainz Dermatologic Surgeon

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Botox for Hyperhidrosis

Botox for hyperhidrosis works very nicely and successfully. It is most ideal for hyperhidrosis of the underarms, less desirable and more painful for hyperhidrosis of the hands and feet. For obvious reasons, people are reluctant to have Botox injected into the palms and soles of the feet - which are sensitive areas of the body. Regardless of the area injected, it has an immediate effect and lasts for as long as 6 months.


BOTOX interferes with the transmission of signals that are sent to your glands and muscles. This is how it reduces excessive sweating. Treatment of hyperhidrosis with Botox is FDA approved and it is not in an "experiential" phase.

Botox for Hyperhydrosis

Hyperhydrosis is a condition that involves excessive sweating, which is sometimes accompanied by bad odor and unsightly dampness.  Usually, underarm sweating is effectively managed with topical, over the counter antiperspirants.  When this does not effectively treat perspiration, from Hyperhidrosis, Botox may provide relief. 

Botox is an FDA approved treatment for Hyperhydrosis that helps control excessive sweating by temporarily blocking chemical signals from the nerves that stimulate sweat glands.  When the sweat glands do not receive chemical signals to sweat - the amount of perspiration is reduced.  Self-confidence is increased when excessive sweating is finally under control. 

100 units of Botox Cosmetic is injected through a very small needle, into the skin of each underarm.  The treatment will hinder the nerve endings of the motor endplates.  The Botox injections will not only cease the excessive sweating, but it will also provide a simultaneous disappearance of the odor associated with the excessive perspiration. 

The results from Botox are not permanent, however.  Results will start to appear during the first few weeks after treatment.  You will be able to enjoy up to 8 months (or longer) of dryness, and reduced odor.  After this time period, a repeat Botox Cosmetic treatment will be necessary.


Botox works very well for under arm excess perspiration

Botox is the gold standard to treat excess sweating (hyperhidrosis) under the arms.  An oral medication (Robinul) can be used in conjunction with Certain-Dri with good effect.  Iontophoresis can also be helpful, but under the arms, Botox works best.

Charles Crutchfield, MD
Minneapolis Dermatologic Surgeon
4.0 out of 5 stars 10 reviews

Botox for Hyperhidrosis

Botox is an FDA approved drug for treatment of excess sweating in areas like the underarms, hands and feet.  The efficacy of the treatment varies so patient selection is key.

Kris M. Reddy, MD, FACS
West Palm Beach Plastic Surgeon
4.5 out of 5 stars 21 reviews

Hyperhydrosis cures

Botox can be a great regimen to use for excessive sweating. Many of my patients rave about their dramatic and “sweet smelling” results! I highly recommended that you first try a heavier antiperspirant, such as Dry Sol. Your doctor may also prescribe topical creams or pills. If all fails you may be diagnosed with hyperhydrosis. Either way, excessive sweating can be easily improved with Botox. Although it is a bit pricey, after tests the insurance companies will make you go through, they may or may not cover it. The results of Botox will last about 6 months. Botox treatments twice a year will most likely be a sufficient amount. If you think Botox will save you the aggravation of expecting a smell by lunch time than you should go for it! Hopefully your doctor will work with you to make it affordable or covered by your insurance

Yael Halaas, MD
Manhattan Facial Plastic Surgeon
4.5 out of 5 stars 28 reviews

Botox can be VERY effective for hyperhidrosis!

Botox can absolutely work very well in treating Hyperhidrosis. In particular, excessive sweating of the underarm (axillary Hyperhidrosis) can be effectively reduced or even eliminated by Botox. I have had so many patients who are thrilled by the results and wish they had discovered this option earlier in their lives.

Hope this helps!

Dr. Y

Haresh Yalamanchili, MD
Houston Facial Plastic Surgeon
4.5 out of 5 stars 14 reviews

Botox for Hyperhidrosis works!

Botox works well for Hyperhidrosis.  50 units per axilla can reduce sweating for several months.

Robert Sleightholm, MD
Brampton Plastic Surgeon
5.0 out of 5 stars 5 reviews

Botox to underarms to decrease sweating

Botox injected to the underarms is definitely effective. It is a great treatment for hyperhydrosis, or excess sweating, and is even requested by patients with "normal sweating". Typically patients are very satisfied with the procedure, and are grateful to save money on new clothing (for "pit stains"), and on dry cleaning. Keep in mind the typical treatment is around 100 units of Botox (50 for each underam), so it costs more than the usual amount used for cosmetic purposes to decrease wrinkles on the face.

Anita Patel, MD
Beverly Hills Plastic Surgeon
4.5 out of 5 stars 12 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.