Skin Lightening: Q&A
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Hydroquinone and Ochronosis For Skin Lightening?
I have olive complexion. My doctor presribed a custom formula for skin lightening containing Hydroquinone 8%, tretinoin .1%, hydrocortisone .5%, and clindamycin 1%. I read on the internet about skin darkening (ochronosis) with hydroquinone use. I would like to try using the presription but am worried about this side effect. How likely is it to happen? Are there steps to prevent this from happening like using it intermittently once I have acheived a good skin tone? Taking breaks, etc? Thank you!
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2 Doctor Answers |
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142683anon
in Denver
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Hydroquinone and Ochronosis For Skin Lightening?
Thank you for your question. Any bleaching creams including hydroquinone should be used for a maximum of 2-3 months and then discontinued. You may take a break for 3 months and then resume usage. Once your skin has lightened in color the best thing to do would be to avoid sun exposure and then to use an sunscreen with SPF 30 with zinc oxide to protect your skin and prevent it from re-darkening. You may need a maintenance program. Be certain to be under the supervision of a board...
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Do not use for more than 6 months
Hydroquinone is a bleaching agent that specifically inhibits the enzyme homogentisic acid oxidase, which can in cetain patients result in the accumulation of this substance on the collagen fibers in tissues where it is applied. This reaction over long term use can result in grey brown and bluish black patches and bumps over the cheeks and forehead called exogenous ochronosis. The majority of patients affected with this reaction have darker skin tones, and...
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Naples Dermatologist
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