OK to Take Cymbalta While on Accutane?

    There is not problem with Cymbalta per se. In other words there is no drug interaction that  am aware of. However, since Cymbalta is meant to treat severe depression, I would engage in a thorough discussion with your dermatologist before continuing.    I have used Accutane a few times in patients with clinical depression. But I kept my fingers crossed with each prescription. Each time we were careful to call the patient twice a week to make... more