Botox: Q&A
Ask a QuestionWhat is the Most Common Amount of Saline Mixture to Powder Constitution of Botox?
what is the most common mixture of Saline cc's to Botox powder constitution?
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10 Doctor Answers |
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1732anon
in Philadelphia
+2
Botulinum Toxin (Dysport or Botox) dilution and preparation
We use 2.5cc of Saline to each vial of Botulinum Toxin as suggested in the package insert for a total of 40 units per 1.0 cc. However according to personal preference, it can be mixed witjh 1-5 cc.
+2
Botox dilution
Botox comes as a frozen powder and must be reconstituted. There are differing opinions on what amount of diluent should be mixed with the powered botox. The botox powder comes in 50 unit and 100 unit vials. Some the of the accepted dilution amounts include 1cc per 100units, 2cc, 2.5cc, 3cc and 4cc per 100 units. Some European and South American physicians will use up to 6 cc per 100 units.
The argument for a more dilute botox reconstitution (4cc-6cc per 100 units) is more botox...
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Toronto Plastic Surgeon
+2
Botox Dilution Rate
The most common dilution rate is 2.5 cc's of saline solution per 100 units of Botox. If you are a consumer, we would be more interested in the number of Botox units injected as opposed to the dilution rate. The number of units injected is the best way to understand how the treatment you are receiving compares with that of other offices. Good luck.
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+2
Botox reconstitution
We use 2cc of saline to reconstitute our Botox for facial injections and 5cc for underarm sweating. The greater amount that you use the greater the risk for diffusion into an area that you may not want to treat. (ie eyelid, brow).
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Botox dilution
I think there is no specific standard. It is all about comfort. I personaly dilute about 2 cc's to keep it well concentrated so that it is about 50 units/cc. Some dilute it more to be a total of 4 cc's so that it is 25 units/cc.
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Dilutions will vary
This is a very good question. There are a lot of variations in the dilutions used amongst physicians. I use 2.5cc as my most common dilution but will adjust this for sensitive areas such as around the mouth/lips. Many other physicians also use this 2.5cc dilution. Some however, prefer 2cc or 4-5cc. some even use a 1cc dilution for certain areas. The actual dilution is not as important as how many units are placed and the physicians experience using...
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+2
Saline Dilution of Botox
I always dilute a 100 unit vial of Botox with 2.5cc of saline. This is, however, an individual physician's choice. The most common dilution is probably 2.5cc. You should inquire about the cost per unit rather than per cc. This way you can compare costs more easily.
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There is a range of dilutions that are considered acceptable.
In the instructions that come with the BOTOX vial, doctors are instructed to dilute the BOTOX with 2 to 4 ml of sterile saline. As you can see from the other responses, some doctors use more saline and there are other who only use 1 ml of saline. However the most common dilutions are in the 2 to 4 ml range.
This means that when the doctor draws up the Botox solution into a one milliliter syringe, the syringe can literally hold any amount of Botox from 100 units,...
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+2
Botox Reconstitution
The most standard dilution used for Botox is 5cc per 100 units, or 2u per 0.1cc. This is what the manufacturer recommends in its packaging, but it can me reconstituted from as little as 1cc to 10cc.
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100 units of Botox is reconstituted with 2cc of preserved saline at my office
Vials of Botox come in 50 unit and 100 unit vials. I find the best amount of saline added is 2cc per 100 units. I also add the preserved saline because it is less painful when administered. Some docs will use 1cc per 100 units and some will add up to 4cc. The less saline used, the less diffusion (movement away from the injected area).
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.
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