Lip Augmentation Q&A
61%
WORTH IT RATING
"Worth It Rating" shows the % of consumer reviewers that stated the procedure was "Worth It" or not. See more RealSelf Worth It Ratings or Add Your Review
108 Reviews
Lip Augmentationbefore & after photos
View Before and Afters

Average Lip Augmentation Cost: $775

Learn about Lip Augmentation

555 people and 388 doctors are talking about Lip Augmentation

Get Free Email Updates

Collagen Vs. Restylane, Which is Best for Lips?

asked 4 years ago by anon
Latest answer by Joseph Mele, MD
Question viewed 1,940 times
Tags: best, comparison

24 answers to Collagen Vs. Restylane, Which is Best for Lips?

+1

HA fillers vs. Collagen - It's No Contest

HA fillers, in the United Stated sold as Restylane, Perlane and Juvederm have completely replaced Collagen. Allergan, which sells Juvederm and sold Collagen, has stopped production of Collagen. With the introduction of HA fillers, the demand for Collagen evaporated. HA filler are softer, more compliant and last longer. It's ease of use is about the same as Collagen. Collagen was better for stubborn fine lines at the margins of the lips, but it lasted only 3 months (or less) time.... more
Joseph Mele, MD

Walnut Creek Plastic Surgeon
+1

For temporary lip enlargement, hyaluronic acid (HA) fillers are best; just say "No!" to collagen.

I too have abandoned collagen products in my practice, though I used them very sucessfully for years. There is nothing inherently "wrong" with collagen products, especially the newer ones that do not require allergic skin testing. It's just that the HA fillers are better, easier to use, and last longer. For these reasons, most of us have decided to use the HA fillers, though collagen may be appropriate for a lower-cost more-temporary fix. With any injectable filler... more
Richard H. Tholen, MD, FACS

Minneapolis Plastic Surgeon
+1

Lip augmentation with collagen or restylane?

I favor the more recent hyaluronic acid fillers such as Juvederm or Restylane. Results are excellent and risks are minimal.
Steven Hacker, MD

West Palm Beach Dermatologic Surgeon
+1

Hyaluronic Acid Fillers best for lips

Traditionally, Collagen fillers (such as cosmoplast and cosmoderm) were used for fine lines around the mouth, while Hyaluronic acids were used to plump up the lips.  While collagen does not last as long as Hyaluronic acids, it was ideal for fine lines since it could be injected superficially and less likely to cause bluish bumps when injected into fine lines.  That was how most of us used these fillers-- until collagen fillers were no longer readily available in the US. We... more
Margaret Mann, MD

Cleveland Dermatologic Surgeon
+1

Collagen Versus Restylane For Lip Enhancement

I have not carried collagen for over 8 years now. I would definitely recommend Restylane or Juvederm before any collagen products. Collagen simply doesn't last long enough in most patients. In some patients, it has gone away as quickly as a few weeks. Restylane and Juvederm are the most popular fillers for lip enhancement at this time and can last upwards of 9 months in many cases.
John M. Hilinski, MD

San Diego Facial Plastic Surgeon
+1

Collagen or Hylan- Kollagen oder Juvederm / Restylane für Lippen

In unserer Praxis bevorzugen wir Juvederm für die Lippenbehandlung, weil die guten Ergebnisse länger anhalten. Außerdem kann das Hyalurongel innerhalb einiger Stunden wieder aufgelöst werden, was unseren Patienten zusätzliche Sicherheit gibt. In our clinic we prefer Juvederm for treating the lips, because the good results last longer than Collagen. Additionally Juvederm can be dissolved within hours with a hyaluronidase treatment, which gives our patients... more
Robert Kasten, MD

Mainz Dermatologic Surgeon
+1

Hyaluronic fillers are best for lips

Collagen is not used much anymore. The hyaluronic fillers (Juvederm, Restylane) last many months longer than collagen and give a softer feel.
Susan Van Dyke, MD

Paradise Valley Dermatologist

www.vandykelaser.com

+1

Restylane or Juvederm is great for lip augmentation

General filler such as Restylane and Juvederm is preferred for lip enhance because it feels soft and natural. This also will last approximately 6 months or more before a refill is required.  Collagen on the other hand requires an allergy test and it will only last 3-4 months.  Cost is also a factor as Juvederm is usually less expensive. 
David A. F. Ellis, MD

Toronto Facial Plastic Surgeon
+1

Hyaluronic acid filler ideal for lip augmentation

The old bovine based collagen is not advisable for its use for lip augmentation as I have seen allergic reaction after 2 negative allergy test. Hyaluronic acid filler on the other hand has minimal allergic potential and can be reversed with hyaluronidase.
William Ting, MD

Bay Area Dermatologic Surgeon
+1

Restylane vs. Collagen for lip augmentation

I have not injected Collagen for years.   Restylane and other Hyaluronic Acid fillers are soooooo much better.  They last longer, are really smooth and don't require a skin test.  Back in the Collagen days, I did not like doing fillers at all.  Now it is one of  my favorite procedures because the results are so pleasing.  Most HA fillers now come with lidocaine (a local anesthetic) and injecting the lips is not so painful.  I really like... more
Lisa L. Sowder, MD

Seattle Plastic Surgeon
+1

Restylane or Juvederm (HA fillers) for lips

Hyaluronic acid fillers are much more commonly used today than collagen. HA fillers do not require skin testing and have very low incidence of allergy or intolerance. Smaller molecule formulations like Restylane and Juvederm work well in the lip to either accentuate the vermillion border, evert the lip or add bulk to the body of the lip. Their effects last 6-9 months. They can be reversed with hyaluronidase if necessary due to asymmetry or clumping of the material. The need to reverse HA... more
Stephen Weber, MD

Lone Tree Facial Plastic Surgeon
+1

Restylane and Juvederm for lips

I would recommend Restylane and Juvederm. These fillers can last up to 9 months and will give you the results you want.
Kimberly A. Henry, MD

Greenbrae Plastic Surgeon
+1

Ideal lip augmentation product

There are a number of injectable products available for lip augmentation.  Currently collagen is hardly used, as it dissipates rather quickly.  Restylane is a good choice, there are other similar products that might last a little longer.  The larger the molecule the more cross linked the longer it will last.  Please discuss with your doctor ideal product.  There are also some more permanent product available, but with a somewhat higher complication profile. more
Boris M. Ackerman, MD

Newport Beach Plastic Surgeon
+1

Restylane is great for lips

I prefer Restylane over collagen for the lips as it is clear, soft, injected through a tiny needle, and integrates nicely into you own tissues.
Randy J. Buckspan, MD

Austin Plastic Surgeon
+1

Collagen versus Restylane in the lips

Today, there are many good options for lip augmentation. In our practice, our patients tend to prefer hyaluronic acid-based fillers such as Restylane and Juvederm. These fillers can last from 6 to 9 months and avoid the risk of reaction or excess inflammation that can be seen with collagen fillers. In our practice, patients receive these fillers with either local anesthesia or a regional bloc so that their treatment is pain-free.  
B. Pat Pazmino, MD

Miami Plastic Surgeon
+1

Best Lip Filler

I prefer the Hyaluronic Acid fillers (Juvederm, Restylane) for the lips-- they give a more natural feel and look, and last longer than collagen.  I generally reserve collagen for the finer lips around the mouth ("smokers lines") or to give additional highlight to the lip border, if needed, after filling with Juvederm or Restylane.
Jeffrey C. Poole, MD

Metairie Dermatologic Surgeon
+1

Collagen Injections Relegated to History

Collagen, in the lips or anywhere for that matter, is almost completely obsolete.  Collagen works well but has such a brief duration that rarely would someone choose it over a hyaluronic filler (Restylane/Juvederm).  Hyaluronic fillers are equal to or better than collagen in almost every respect.  Perhaps collagen is better at filling extremely fine wrinkles, but that is debatable.  Rarely are people interested in the monthly re-treatment schedule necessary to maintain... more
Louis W. Apostolakis, MD

Austin Facial Plastic Surgeon
+1

Best filler choice for lips

My pick is hyaluronic acid and at this date most often Juvederm because it is easy to inject, is very smooth and has a low profile for swelling. Plus the fact that it lasts considerably longer than collagen. But, collagen is better (again at this date) for the fine vertical lines above the lip. This is a temporary fix, but the lipstick lines are very often a distressing appearance issue for women who have the problem, whether from being previous smokers or from habitual pursing of the lips.... more
Rebecca Fitzgerald, MD

Los Angeles Dermatologist
+1

Hyaluronic acid is better in the lips than collagen

If you are given the choice hyaluronic acid gels like Restylane or Juvederm are far superior to collagen products. They are reliable, soft and equivalent in price. I would say that Juvederm Ultraplus is a great option in the hands of someone who knows how and where to inject it. I hope this helps and let me know if you have any further questions.
Andrew P. Trussler, MD

Dallas Plastic Surgeon
+1

Restylane is Better

Collagen lip augmentation has almost become a historical procedure. I haven't used a non-hyaluronic acid filler in the lips since FDA approved Restylane became available in the United States. The primary reasons are result and longevity. Restylane (a hyaluronic acid filler like Juvederm, Hydrelle, etc) is hydrophilic and leaves a soft, plump look to the lips, lasting 4-6 months. Collagen lasts about a month and is firmer to touch
Stephen Prendiville, MD

Fort Myers Facial Plastic Surgeon
+1

Combination

Collagen is a bit firmer than Restylane and gives better support to the vermilion border of the lip. It is also somewhat superior for eradicating smoker's lines. However, the present available collagens (Cosmoderm, Zyderm) only last about 3 months. The hyaluronic fillers, Juvederm Plus, Restylane, and Prevelle, are quite a bit better when it comes to augmenting the lip itself. They also last longer. When Evolence Breeze is approved, patients will get the both of both worlds.... more
Arnold R. Oppenheim, MD

Virginia Beach Dermatologist
+1

Collagen not used often

Collagen is really not used very often anymore because its results dont last that long. With the new HA the results can last up to 4-6 months as compared to a couple of months with collagen. Therefore most plastic surgeons would use restylane or juvederm in the lip for lines and augmentation.
Farbod Esmailian, MD

Orange County Plastic Surgeon
+1

Sometimes you need both Collage and Restylane

Typically, injections with a hyaluronic acid such as Restylane will give you a natural- appearing lip plumping that will last 4-6 months. Small amounts can be used to improve the definition of the border of the upper lip (the vermilion border), while larger amounts will make the lips more full and youthful. Restylane in the lips can also be used to correct for a downward turning mouth. Collagen, on the other hand, is preferred by some doctors to fill individual vertical lip lines... more
Randolph Capone, MD

Baltimore Facial Plastic Surgeon
+1

Restylane or other Hyaluronic Acids

Definitely one of the hyaluronic acids are the injectables that we prefer for lip enhancement in our practice.  These include Juvederm, Perlane and Restylane although other injectables are certainly on the horizon.
S. Randolph Waldman, MD

Lexington Facial Plastic Surgeon

Ask a question