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Can I Get a Chemical Peel Before Accutane?

I am 29-years-old and I have melasma on my cheeks and upper lip and I absolutley hate it, especially on my upper lip. I also am suffering from acne and would like to try Accutane. I know Accutane is usually a six month treatment and I would have to wait quite a while after for a chemical peel. My question is can I get a chemical peel to help the melasma before I start the Accutane, and if so how long between the two?

Doctor Answers (3)

Chemical Peels and Accutane


Superficial Peeling agents, when not overly aggressive, are fine to use during Isotretinoin (Accutane) treatment-- my preferred or your condition being Jessner's Solution or Salicylic Acid.  Make sure the peels are performed by in a Board Certified Physicians office by an experienced practitioner.

Deeper peeling with medium depth peeling agents-- combination peels, often using TCA or phenol- should be allowed to fully heal prior to starting Isotretinoin, normally about 2 weeks.

Metairie Dermatologic Surgeon
5.0 out of 5 stars 3 reviews

Chemical peel for melasma before Accutane


One of the best peels for melasma is the Vi Peel which has a small amount of phenol and ingredient that is very helpful for treating unwanted dark marks.  Let your skin recover for at least 2 weeks before starting isotretioin (Accutane).  It would be best to get the peel in a board-certified dermatologist's office if you are considering getting Accutane after.  Good luck!

Dina D. Strachan, MD
New York Dermatologist
3.5 out of 5 stars 9 reviews



Yes- try a few very light Glycolic peels. I usually start my patients with %20, then $25%, %30 and maybe even %50 glycolic peels. Please do it in a doctors office. In addition you should use SPF 30 and a bleaching cream (2% Hydroquinone). These treatments are safe even while on Accutane.

A. David Rahimi, MD
Los Angeles Dermatologist
5.0 out of 5 stars 35 reviews

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