Is There Any Chance That Latisse Can Cause Blue Eyes to Turn Brown?

There is no evidence to suggest that Latisse will change your eye color. The eye is exposed to a very small amount of Latisse even when it is properly applied as directed to the upper eyelid margin using the supplied applicator. This has been demonstrated by applying a colored dye to the eyelid margin and watching its migration. Over two million prescriptions for Latisse have been filled with no confirmed reports of iris pigmentation issues. Side effects from the initial studies showed less... more

Latisse can cause a darkening of the iris or eyelid margin.  Have your eyes checked before you begin and after so you can be closely monitored.  The change in color may be permanent.  The only way to ensure that this will not occur is to not use the Latisse.  According to the product insert, this side effect was not observed in the Latisse study but has been observed with the medicine if instilled in the eye for the treatment of glaucoma.