The Cellulaze procedure can be done under local anesthesia in most cases
If you would do OK getting a root canal without anesthesia, then perhaps you could handle Cellulaze without anesthesia. But seriously, this is a laser (hot) moved back and forth under your skin for hours. Local anesthesia is fine for limited areas, but if you're getting several areas done, the local anesthesia must be diluted to keep within a safe dose, and so a more systemic anesthesia is needed, i.e. IV sedation, "twilight" anesthesia, or even general anesthesia.