Can Botox treat hyperhidrosis?

Can Botox treat hyperhidrosis? Is this Botox hyperhidrosis treatment approved by the FDA or just experimental?

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21 answers to “Can Botox treat hyperhidrosis?”

A: Botox is a great, but temporary treatment for hyperhydrosis

Stephen Prendiville, MD

Botox®, the commercially available form of Botulinum toxin type A, is a very effective, but temporary treatment for hyperhydrosis (sweaty palms, sweaty armpits, etc).  The reason for this is that the receptor that activates the sweat gland is very similar to the one that exists between motor nerves... more

A: Absolutely. Botox is an excellent treatment for under...

Robert W. Kessler, MD

Absolutely. Botox is an excellent treatment for under arm hyperhidrosis. Excess under arm sweating can be diagnosed with a simple in office exam using iodine and starch powder. The area is then injected with Botox just below the surface of the skin, covering the entire area of staining. Typically 50 units are... more

A: Botox, or botulinum toxin type A, was approved by the...

D.J. Verret, MD

Botox, or botulinum toxin type A, was approved by the FDA in 2004 for the treatment of severe primary axillary hyperhidrosis (excessive underarm sweating) that is inadequately managed with topical agents. Botox can also be used for excess sweating in other areas, though this is technically an off-label use... more

A: Botox for Excessive Sweating (hyperhydrosis) of Underarms or Palms of Hands

Michael Law, MD

The social embarrassment associated with excessive sweating can be profound. Whether the problem is primarily underarm sweating or palmar sweating, or both, the impact on normal social interaction can be significant. Some individuals with excessive underarm sweat production wear special pads and garments to... more

A: Botox is a great way to treat...

Jordana S. Gilman, MD

Botox is a great way to treat hyperhidrosis! Hyperhidrosis is a medical condition where people sweat excessively, in situations unrelated to the temperature/weather. It is most common under the arms and on the palms and soles, and can cause a lot of anxiety in those affected. Botox is FDA-approved to treat... more

A: Botox is great for sweating

Steven F. Weiner, MD

Botox works by inhibiting a neurotransmitter, Acetylcholine, from being released.  This happens to be the same neurotransmiiter used for moving muscles, and to produce sweat.  It shouldn't be the first thing you try for excessive sweating, but if everything else fails, it's great for underarms, hands... more

A: Botox for axillary hyperhidrosis

Pramit Malhotra, MD

Typcial results from Botox injections to the armpit area is a 50-80% reduction in sweat production. This is often the perfect amount since some sweat function in this area is essential as a normal process of your body.  The armpit skin isn't that sensitive, and patients tolerate it very well, by evidence,... more

A: Botox for hyperhidrosis - Relief for 7-17 months!

Laurie Polis, MD

Botox is an amazing and effective treatment for hyperhidrosis (excessive perspiration). We utilize it most commonly for the axillae (underarms) but also use it for the palms, soles and for focal areas in which patients complain of sweating, such as the forehead. It works by diminishing the sweat secretions of... more

A: Botox

Wilfred Brown, MD

Botulinum Toxin (Botox (R)) is a very successful method of treating hyperhydrosis. It is generally given in a grid-like pattern in the area to be treated. The Botox (R) is given intradermally with a fine gauge needle, and is minimally painful. Hyperhydrosis is an FDA approved indication for Botox (R) where... more

A: Botox for underarm hyperhidrosis

Hratch Karamanoukian, MD

Botox for hyperhidrosis of the underarms can be very effective and is one of the areas of the body where as little as 2 needle sticks can get rid of excessive sweating anywhere from 3 months to 6 months or more. Once the individual becomes tired of repeated injection, or in the rare situation where the... more

Comments

alyarand
4 posts
4 Jun 2008

Botox is FDA approved to treat primary axillary (arm pit) hyperhidrosis. It was approved for this indication in July of 2004. The drug blocks the nerve function to the nerves that stimulate sweating. When a practitioner performs this procedure, he or she normally dilutes it more than he or she would when treating wrinkles on the face. This allows more diffusion of the product in the area being treated. Some practitioners sprinkle corn starch in the area prior to injecting, which turns purple-colored in the areas that are most actively producing sweat. We then can make sure to focus our injections in those locations before moving on to the rest of the area.  Sweating in the treated areas is usually significantly reduced for up to 6 months.  Off-label use for Botox treatment for hyperhidrosis includes injecting the palms and soles, which works great but is often quite uncomfortable to receive.  Some insurance companies will pay for Botox injections under the arms when the physician/PA/NP documents treatment failure on other, less costly prescriptions (such as Dry-Sol, for example).

dverebelyi
81 posts
9 May 2008

Botox is extremely effective for Hyperhidrosis.  According to a study published in The Journal of Drugs and Dermatology this year that compared Aluminum Chloride deodorants (Drysol) to Botox, patients had 92% satisfaction with Botox vs. only 29% with the Aluminum Chloride deodorant after 4 weeks.  Injections done by a qualified practictioner cause minimal discomfort and effects normally last about 6 months.

Michael Sinclair MD
134 posts
11 May 2008

Hyperhydrosis, also known as excessive sweating, can range from mild to extreme. When hyperhidrosis is extreme, it is not just an annoying condition, it can be disabling. The excessive sweating of the hands can make it difficult to work. When it affects the underarms, it can drench your clothes in sweat. When it affects the feet, it can lead to horrible fungal infections which make even walking difficult. Treatment with Botox is FDA approved and very effective. Some insurance companies may even be willing to reimburse you for the cost of treatment. If you intend to try to get reimbursement from your insurance company, be aware that there are a few hoops you need to jump through to have a chance at getting some money back. First, make sure the doctor uses a vial of Botox that is specifically labeled for therapeutic use. The therapeutic vials and the cosmetic vials both contain exactly 100 units of Botox, but the therapeutic vials have a different NDC number. I have seen some insurance companies reject the claim because the wrong NDC  number was submitted. (In my opinion, that sort of rejection is completely unethical, but insurance companies are in the business of making money, not in the business of helping people). Second, make sure you have tried some other treatment, such as drysol applied to the affected area. Again, insurance companies may reject your claim unless you have tried and failed using some less expensive alternative before you try Botox. Botox can be injected into axilla (underarms) with very little discomfort. I use a 33 guage needle, which makes it almost painless. On the otherhand, Botox injections into the palms or soles is very painful. In order to inject these areas, I perform a nerve block. The nerve block is very effective, but it might make your hands or feet too numb to drive home, so make sure you have a driver to take you home after the treatment. Michael Sinclair, MD

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